Document Detail

Evaluation of antifungal properties of octyl gallate and its synergy with cinnamaldehyde.
MedLine Citation:
PMID:  16750625     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to investigate the possibility of using octyl gallate alone or with organic biocides as a preservative against wood decay fungi. Antifungal activities of three antioxidants, propyl gallate, octyl gallate and butylated hydroxyltoluene (BHT) were tested against four wood decay fungi, Lenzites betulina, Trametes versicolor, Gloeophyllum trabeum and Laetiporus sulphureus. Octyl gallate was found to be the only active compound with IC50 values of 0.47, 0.16, 0.24 and 0.04 mM against L. betulina, T. versicolor, G. trabeum and L. sulphureus, respectively. A synergistic effect was also found when octyl gallate was combined with cinnamaldehyde. Results obtained herein demonstrated that octyl gallate by itself exhibited an excellent antifungal property and enhanced protection was further observed by combining it with cinnamaldehyde.
Fu-Lan Hsu; Hui-Ting Chang; Shang-Tzen Chang
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Publication Detail:
Type:  Journal Article     Date:  2006-06-05
Journal Detail:
Title:  Bioresource technology     Volume:  98     ISSN:  0960-8524     ISO Abbreviation:  Bioresour. Technol.     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2006-09-20     Completed Date:  2007-02-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9889523     Medline TA:  Bioresour Technol     Country:  England    
Other Details:
Languages:  eng     Pagination:  734-8     Citation Subset:  IM    
School of Forestry and Resource Conservation, National Taiwan University, Taipei 106, Taiwan, ROC.
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MeSH Terms
Acrolein / analogs & derivatives*,  pharmacology
Antifungal Agents / pharmacology*
Basidiomycota / drug effects
Drug Evaluation, Preclinical
Drug Synergism
Free Radical Scavengers / pharmacology
Gallic Acid / analogs & derivatives*,  pharmacology
Microbial Sensitivity Tests
Reg. No./Substance:
0/Antifungal Agents; 0/Free Radical Scavengers; 1034-01-1/octyl gallate; 104-55-2/cinnamic aldehyde; 107-02-8/Acrolein; 149-91-7/Gallic Acid

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