| Evaluation of the anticancer activities of Tweens 20, 40 and 60 in SJL/J mice. | |
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MedLine Citation:
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PMID: 2018377 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tween 20 (polyoxyethylenesorbitan monolaurate), Tween 40 (polyoxyethylenesorbitan monopalmitate), and Tween 60 (polyoxyethylenesorbitan monostearate) were found to have little activity against development of reticulum cell sarcoma in SJL/J mice. These findings resulted in studies to explain the previous observation that Tween 80 (polyoxyethylenesorbitan monooleate) has anticancer activity in the SJL/J tumor system. Evidence is presented to suggest that the apparent difference may be related to the fatty acid component (saturated or unsaturated) of the Tween. |
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Authors:
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C G Crispens; J R Sorenson |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Anticancer research Volume: 11 ISSN: 0250-7005 ISO Abbreviation: Anticancer Res. Publication Date: 1991 Jan-Feb |
Date Detail:
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Created Date: 1991-05-23 Completed Date: 1991-05-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8102988 Medline TA: Anticancer Res Country: GREECE |
Other Details:
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Languages: eng Pagination: 407-8 Citation Subset: IM |
Affiliation:
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Department of Biology, University of Alabama, Birmingham 35294. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antineoplastic Agents* Female Lymphoma, Large B-Cell, Diffuse / prevention & control* Mice Mice, Inbred Strains Polysorbates / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents; 0/Polysorbates; 9005-66-7/polysorbate 40 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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