Document Detail


Evaluation of antibacterial soap in the management of lymphoedema in Leogane, Haiti.
MedLine Citation:
PMID:  20850849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In areas endemic for lymphatic filariasis, progression of lymphoedema is associated with recurrent bacterial acute dermatolymphangioadenitis (ADLA). The role of antibacterial soap in preventing ADLA is unknown. In a randomized double-blinded clinical trial in Leogane, Haiti, lymphoedema patients washed affected legs with antibacterial (n = 97) or plain soap (n = 100). Reported ADLA incidence (by recall) before the study was 1.1 episodes per person-year, compared to 0.40 assessed during the 12-month study. ADLA incidence was significantly associated with age, illiteracy and lymphoedema stage, but not with soap type. Washing with soap, regardless of its antibacterial content, can help decrease ADLA incidence. (ClinicalTrials.gov identifier number NCT00139100.).
Authors:
David G Addiss; Marie-Carmel Michel; Antoine Michelus; Jeanne Radday; Ward Billhimer; Jacky Louis-Charles; Jacquelin M Roberts; Kathy Kramp; Benjamin A Dahl; Bruce Keswick
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2010-09-17
Journal Detail:
Title:  Transactions of the Royal Society of Tropical Medicine and Hygiene     Volume:  105     ISSN:  1878-3503     ISO Abbreviation:  Trans. R. Soc. Trop. Med. Hyg.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-03     Completed Date:  2011-04-11     Revised Date:  2011-06-01    
Medline Journal Info:
Nlm Unique ID:  7506129     Medline TA:  Trans R Soc Trop Med Hyg     Country:  England    
Other Details:
Languages:  eng     Pagination:  58-60     Citation Subset:  IM    
Copyright Information:
Published by Elsevier Ltd.
Affiliation:
Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. dgaddiss@yahoo.com
Data Bank Information
Bank Name/Acc. No.:
ClinicalTrials.gov/NCT00139100
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Bacterial Agents / therapeutic use*
Elephantiasis, Filarial / complications,  epidemiology,  prevention & control*
Female
Haiti / epidemiology
Humans
Lymphedema / epidemiology,  etiology,  prevention & control*
Male
Soaps / therapeutic use*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Soaps

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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