| Evaluation of antibacterial soap in the management of lymphoedema in Leogane, Haiti. | |
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MedLine Citation:
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PMID: 20850849 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In areas endemic for lymphatic filariasis, progression of lymphoedema is associated with recurrent bacterial acute dermatolymphangioadenitis (ADLA). The role of antibacterial soap in preventing ADLA is unknown. In a randomized double-blinded clinical trial in Leogane, Haiti, lymphoedema patients washed affected legs with antibacterial (n = 97) or plain soap (n = 100). Reported ADLA incidence (by recall) before the study was 1.1 episodes per person-year, compared to 0.40 assessed during the 12-month study. ADLA incidence was significantly associated with age, illiteracy and lymphoedema stage, but not with soap type. Washing with soap, regardless of its antibacterial content, can help decrease ADLA incidence. (ClinicalTrials.gov identifier number NCT00139100.). |
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Authors:
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David G Addiss; Marie-Carmel Michel; Antoine Michelus; Jeanne Radday; Ward Billhimer; Jacky Louis-Charles; Jacquelin M Roberts; Kathy Kramp; Benjamin A Dahl; Bruce Keswick |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial Date: 2010-09-17 |
Journal Detail:
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Title: Transactions of the Royal Society of Tropical Medicine and Hygiene Volume: 105 ISSN: 1878-3503 ISO Abbreviation: Trans. R. Soc. Trop. Med. Hyg. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-03 Completed Date: 2011-04-11 Revised Date: 2011-06-01 |
Medline Journal Info:
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Nlm Unique ID: 7506129 Medline TA: Trans R Soc Trop Med Hyg Country: England |
Other Details:
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Languages: eng Pagination: 58-60 Citation Subset: IM |
Copyright Information:
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Published by Elsevier Ltd. |
Affiliation:
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Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. dgaddiss@yahoo.com |
| Data Bank Information | |
Bank Name/Acc. No.:
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ClinicalTrials.gov/NCT00139100 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Bacterial Agents / therapeutic use* Elephantiasis, Filarial / complications, epidemiology, prevention & control* Female Haiti / epidemiology Humans Lymphedema / epidemiology, etiology, prevention & control* Male Soaps / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Soaps |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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