Document Detail


Evaluation of anti-inflammatory activity of selected legumes from Pakistan: In vitro inhibition of Cyclooxygenase-2.
MedLine Citation:
PMID:  23261746     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Crude methanolic extracts of selected legumes namely, black gram (Vigna mungo L.), green gram (Vigna radiata (L.) R. Wilczek ), soybean (Glycine max (L.) Merr.) and lentil (Lens culinaris Medik.) were investigated for anti-inflammatory effects, using COX-2 producing PGE(2) inhibitory assay. Percentage inhibition observed was 73.93, 79.84, 92.17 and 74.47 for black gram, green gram, soybean and lentil respectively at 20μg/ml extract concentration. The 100μg/ml concentration showed increase in the percent inhibition except for soybean. This is the first report on COX-2 inhibitory potential of food legumes.
Authors:
Muhammad Ziaul Haq; Premysl Landa; Zsofia Kutil; Mughal Qayum; Shakeel Ahmad
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Pakistan journal of pharmaceutical sciences     Volume:  26     ISSN:  1011-601X     ISO Abbreviation:  Pak J Pharm Sci     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9426356     Medline TA:  Pak J Pharm Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  185-187     Citation Subset:  -    
Affiliation:
Department of Pharmacognosy, University of Karachi, Karachi-75270, Pakistan.
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