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EVALUATION OF ANTE- AND POSTNATAL DIAGNOSTIC CRITERIA FOR TAPS (Twin Anemia Polycythemia Sequence).
MedLine Citation:
PMID:  25484182     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To analyze the relevance of the ante- and postnatal diagnostic parameters of TAPS.
METHODS: Diagnostic data of all cases of TAPS followed in our institution between 2006 and 2013 were reviewed. Statistical analyses were conducted using Bayesian methods.
RESULTS: Twenty cases of TAPS were included. We found a relationship between the hemoglobin level and the MCA-PSV (coefficient -0.25 [-0.34, -0.15], Pr(coef < 0) = 99.99%). Sensitivity and specificity of the antenatal diagnosis were 71% and 50% regarding the correspondence with postnatal diagnosis. There was no correlation between the number (OR = 0.89 [0.72, 1.10], Pr(OR > 1) = 14.8%), the mean diameter (OR = 0.98 [0.32, 3.06], Pr(OR > 1) = 48.9%) or the total diameter (OR = 0.79 [0.36, 1.53], Pr(OR > 1) = 26.3%) of AV anastomoses and the severity of TAPS.
CONCLUSION: MCA-PSV is a reliable tool for estimating the hemoglobin level in cases of TAPS. The correspondence between ante- and postnatal diagnosis is imperfect. Further studies are required to evaluate opportunity of widening postnatal diagnostic criteria. This article is protected by copyright. All rights reserved.
Authors:
Marine Veujoz; Nicolas Sananès; François Severac; Nicolas Meyer; Anne-Sophie Weingertner; Monique Kohler; Fernando Guerra; Adrien Gaudineau; Israël Nisand; Romain Favre
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-12-5
Journal Detail:
Title:  Prenatal diagnosis     Volume:  -     ISSN:  1097-0223     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  2014 Dec 
Date Detail:
Created Date:  2014-12-8     Completed Date:  -     Revised Date:  2014-12-9    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
This article is protected by copyright. All rights reserved.
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