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Evaluation of air-displacement plethysmography for body composition assessment in preterm infants.
MedLine Citation:
PMID:  22669294     Owner:  NLM     Status:  Publisher    
Background:Adiposity may contribute to the future risk of disease. The aim was to evaluate the accuracy and reliability of an air-displacement plethysmography system (ADP) to estimate percentage fat mass (%FM) in preterm infants and to evaluate inter-device reliability in infants.Methods:70 preterm and 9 full term infants were assessed. The accuracy of ADP measurements was assessed by determining reference %FM values using H(2)(18)O dilution measurement.Results:Mean %FM by ADP was 5.67 ± 1.84 and mean % FM by H(2)(18)O dilution was 5.99 ± 2.56. Regression analysis showed that % FM by ADP was associated with %FM by H(2)(18)O dilution (R(2)=0.63,standard error of estimate (SEE)=1.65, P=0.006). Bland-Altman analysis showed no bias (r=-0.48, P=0.16) and 95% limits of agreement were -3.40 to 2.76 %FM. There was no difference in mean inter-device reliability %FM values (8.97 vs. 8.55 %FM) between ADP 1 and 2. Regression analysis indicated a low SEE (1.14% FM), high R(2) (0.91) and 95% limits of agreement were -1.87 to 2.71% FM. The regression line also did not differ significantly from the line of identity.Conclusion:ADP is a noninvasive, reliable, and accurate technique to measure preterm infants' body composition in both research and clinical settings.
Paola Roggero; Maria L Giannì; Orsola Amato; Pasqua Piemontese; Daniela Morniroli; William W Wong; Fabio Mosca
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-05
Journal Detail:
Title:  Pediatric research     Volume:  -     ISSN:  1530-0447     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0100714     Medline TA:  Pediatr Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Maternal and Pediatric Sciences, Fondazione IRCCS "Ca'Granda" Ospedale Maggiore Policlinico, University of Milan, Milan 20122, Italy.
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