| Evaluation of additional amine fluoride/stannous fluoride-containing mouthrinse during supportive therapy in patients with generalized aggressive periodontitis. A randomized, crossover, double-blind, controlled trial. | |
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MedLine Citation:
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PMID: 15312096 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: The objective of the present randomized controlled trial was to evaluate the efficacy of a mouthrinse containing a combination of AmF/SnF2 in controlling supragingival plaque accumulation and gingival inflammation during a 12-week period in patients affected by generalized aggressive periodontitis (GAP). METHODS: Eighteen subjects, six males and 12 females, mean age: 32.2 years, were evaluated. One-half of the patients was either prescribed an AmF/SnF2-containing mouthrinse (test mouthrinse) or a control mouthrinse in addition to mechanical plaque control for 12 weeks. After a 2-week wash-out period, the patients received the alternative mouthrinse. Before and after treatment plaque index (PlI), gingival index (GI), angulated bleeding index (AngBI), tooth stain (GMSI), and tongue stain were recorded. RESULTS: Test mouthrinse resulted in a statistically significant decrease in PlI (p = 0.029) and GI (p = 0.017). After treatment, PlI was significantly lower in test compared to control mouthrinse (p = 0.027). GMSI significantly increased post-treatment for both mouthrinse regimens (p < 0.001), a significantly higher score being observed for the test compared to control mouthrinse (p = 0.002). CONCLUSIONS: The 12-week use of a AmF/SnF2-containing mouthrinse as an adjunct to conventional mechanical oral hygiene procedures in GAP patients was effective in controlling the amount of supragingival plaque deposits. |
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Authors:
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Maria Elena Guarnelli; Francesca Zangari; Roberta Manfrini; Chiara Scapoli; Leonardo Trombelli |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of clinical periodontology Volume: 31 ISSN: 0303-6979 ISO Abbreviation: J. Clin. Periodontol. Publication Date: 2004 Sep |
Date Detail:
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Created Date: 2004-08-17 Completed Date: 2004-11-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0425123 Medline TA: J Clin Periodontol Country: Denmark |
Other Details:
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Languages: eng Pagination: 742-8 Citation Subset: D; IM |
Affiliation:
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Research Center for the Study of Periodontal Diseases, University of Ferrara, Ferrara, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analysis of Variance Cross-Over Studies Dental Plaque / prevention & control* Double-Blind Method Drug Combinations Female Fluorides, Topical / adverse effects, therapeutic use* Gingivitis / prevention & control* Humans Male Mouthwashes / adverse effects, therapeutic use* Periodontal Index Periodontitis / therapy* Statistics, Nonparametric Tin Fluorides / adverse effects, therapeutic use* Tooth Discoloration / chemically induced |
| Chemical | |
Reg. No./Substance:
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0/Drug Combinations; 0/Fluorides, Topical; 0/Mouthwashes; 0/Tin Fluorides; 0/amine fluoride solution |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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