Document Detail

Evaluation of the acoustic function in pseudoexfoliation syndrome and exfoliation glaucoma: audiometric and tympanometric findings.
MedLine Citation:
PMID:  18203088     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Previous studies have reported increased audiometric thresholds in patients with pseudoexfoliation syndrome (XFS), compared with normative data. This study examines mean audiometric thresholds and tympanometric peak values in patients with XFS and in a control group. METHODS: This is a prospective, nonrandomized control case study. Patients with XFS in one or both eyes constituted the study group (SG). Patients without XFS in either eye constituted the control group (CG). Patients with a history of conditions affecting hearing function were excluded. The SG and the CG included 54 and 48 patients, respectively. Pure tone hearing thresholds levels were measured at 0.25, 1, 2, 3, and 8 kHz. Tympanometric peak values were also recorded. Differences in audiometric mean threshold values and tympanometric peak values between SG and CG, as well as between glaucomatous and nonglaucomatous eyes, were examined. RESULTS: Bone and air audiometric thresholds were significantly increased in SG for 3 kHz and 8 kHz but not for 0.25 kHz, 1 kHz, and 2 kHz. Tympanometric peak values were significantly lower in SG compared with CG. In SG, glaucomatous patients had significantly higher air-conduction thresholds for 3 kHz and 8 kHz. Differences in bone and air audiometric findings as well as tympanometric findings between glaucomatous and nonglaucomatous patients were statistically not significant in CG. CONCLUSIONS: The results agree with previous reports on sensorineural hearing loss in XFS. The reduced tympanometric peak values in SG imply impairment in the elastic properties of the middle ear in XFS. The findings provide additional evidence for the systemic nature of XFS.
E T Detorakis; F Chrysochoou; V Paliobei; A G Konstas; V Daniilidis; D Balatsouras; G Kefalidis; V P Kozobolis
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  18     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    2008 Jan-Feb
Date Detail:
Created Date:  2008-01-18     Completed Date:  2008-04-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  71-6     Citation Subset:  IM    
Department of Ophthalmology, University of Heraklion, Crete, Greece.
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MeSH Terms
Acoustic Impedance Tests / methods*
Aged, 80 and over
Audiometry, Pure-Tone / methods*
Auditory Threshold / physiology*
Case-Control Studies
Exfoliation Syndrome / complications,  physiopathology*
Glaucoma, Open-Angle / complications,  physiopathology*
Hearing Loss, Sensorineural / complications,  physiopathology*
Intraocular Pressure
Middle Aged
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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