Document Detail

Evaluation of a system for transcutaneous long-term capnometry.
MedLine Citation:
PMID:  20224249     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The measurement of CO(2) partial pressure (PCO(2)) is of great importance. Former systems of transcutaneous capnometry combining the measurement of oxygen partial pressure (PO(2)) and PCO(2) had their limitations due to skin irritations caused by the heating-up of the sensor and a short application time of 4 h. OBJECTIVES: To evaluate for the first time combined monitoring of transcutaneous PCO(2) (tcPCO(2)) and oxygen saturation applying a lower temperature (sensor temperature 42 degrees C) and a new sensor technology in healthy individuals during sleep. METHODS: Twenty-nine healthy individuals [12 males, age 35.2 +/- 17.0 years, body height: 170.2 +/- 12.0 cm (mean +/- SD), weight: 76.3 +/- 15.8 kg, body mass index 26.5 +/- 5.4] were monitored for more than 6 h at night with the TOSCA 500 instrument (Radiometer, Basel, Switzerland). tcPCO(2) was continuously monitored and its correlation with selective measured capillary PCO(2) values (PcapCO(2)) was monitored at 0.00 and 4.00 h. RESULTS: At 0.00 h, PcapCO(2) was 37.1 +/- 5.1 mm Hg and tcPCO(2) was 43.4 +/- 6.6 mm Hg (p < 0.001). At 4.00 h, PcapCO(2) was 37.0 +/- 5.6 mm Hg and tcPCO(2) was 43.5 +/- 5.4 mm Hg (p < 0.001). PcapCO(2) and tcPCO(2) were positively and significantly correlated (0.00 h: r = 0.5, p < 0.02 and 4.00 h: r = 0.72 and p < 0.001) at both time points. In the course of the night, there was no significant drift in the tcPCO(2) values. CONCLUSION: The investigated system enables stable measurement of tcPCO(2) without relevant drift in healthy individuals and does not require recalibration. tcPCO(2) is highly suitable as a measure of PcapCO(2) because the two parameters are highly correlated and there is no inconvenience to the patient.
Winfried J Randerath; Sven Stieglitz; Wolfgang Galetke; Norbert Anduleit; Marcel Treml; Thorsten Schäfer
Related Documents :
22921489 - Baroreflex control of renal sympathetic nerve activity in mice with cardiac hypertrophy.
7474669 - Long-term effects of reduced renal mass in humans.
6869009 - Intrarenal backflow during retrograde pyelography with graded intrapelvic pressure. a p...
6218939 - The acute hemodynamic effects of a new agent, mdl 17,043, in the treatment of congestiv...
3158689 - Mdl 17,043 therapy in severe congestive heart failure: characterization of the early an...
2350999 - Transducer manometry and the effect of body position on anal canal pressures.
1121509 - Direct effects of hypoosmolality on vascular resistance and myocardial contractile forc...
25327439 - White coat effect and masked uncontrolled hypertension in treated hypertensive-diabetic...
6387759 - Home relaxation techniques for essential hypertension.
Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2010-03-11
Journal Detail:
Title:  Respiration; international review of thoracic diseases     Volume:  80     ISSN:  1423-0356     ISO Abbreviation:  Respiration     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-20     Completed Date:  2010-11-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0137356     Medline TA:  Respiration     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  139-45     Citation Subset:  IM    
Copyright Information:
Copyright 2010 S. Karger AG, Basel.
Institute of Pneumology at the University Witten/Herdecke, Clinic for Pneumology and Allergology, Center of Sleep Medicine and Respiratory Care, Bethanien Hospital, Solingen, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Gas Monitoring, Transcutaneous / instrumentation*
Carbon Dioxide / blood*
Middle Aged
Young Adult
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Reduction of serum retinol-binding protein-4 levels in nondiabetic obstructive sleep apnea patients ...
Next Document:  Maximal exercise capacity in chronic obstructive pulmonary disease: a limited indicator of the healt...