| An Evaluation of Subacute Sclerosing Panencephalitis Patients with Diffusion-Weighted Magnetic Resonance Imaging. | |
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MedLine Citation:
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PMID: 22886232 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: This study aimed to evaluate the contribution of diffusion weighted magnetic resonance imaging to the diagnosis and staging of subacute sclerosing panencephalitis. MATERIAL AND METHOD: The study comprised 26 patients diagnosed with subacute sclerosing panencephalitis at our clinic who were undergoing regular follow-up, and a control group of 18 subjects. Clinical staging was determined by Risk and Haddad classification; 12 at Stage II and 14 at Stage III. Diffusion weighted magnetic resonance images were taken of six areas (frontal, parieto-occipital, cerebellar, deep white matter, thalamus and basal ganglia) and by calculating the apparent diffusion coefficient (ADC) values, and a comparison was made between the stages and with the control group. RESULTS: The ADC values of all the areas of the subacute sclerosing panencephalitis patients were found to be significantly higher compared to the control group (p < 0.05). While the mean ADC values of the deep white matter, basal ganglia, frontal and parieto-occipital areas of the Stage II patients were found to be significant compared to the control group (p < 0.05), there was no significance in the other areas (p > 0.05). The ADC values of all the areas of the Stage III patients were found to be significantly high compared to the Stage II values (p < 0.05). CONCLUSION: Diffusion weighted magnetic resonance imaging can be used with other diagnostic criteria to confirm diagnosis of subacute sclerosing panencephalitis and to reveal differences between the stages. |
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Authors:
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M Abuhandan; H Cece; M Calik; E Karakas; F Dogan; O Karakas |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-12 |
Journal Detail:
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Title: Clinical neuroradiology Volume: - ISSN: 1869-1447 ISO Abbreviation: Clin Neuroradiol Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101526693 Medline TA: Clin Neuroradiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Pediatric, Harran University Medical Faculty, 63100, Sanliurfa, Turkey, drabuhandan@mynet.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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