Document Detail


Evaluation of the i-STAT hand-held chemical analyser during treadmill and endurance exercise.
MedLine Citation:
PMID:  12405749     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study examined the accuracy and precision of a hand-held, chemical analyser, i-STAT, in measuring selected blood constituents which may be of use in the diagnosis and management of metabolic disorders found in exercising horses. Venous blood samples were taken from 3 Thoroughbred geldings, fit and trained to exercise on a treadmill, both before and after exercise at a speed sufficient to elicit VO2max. The samples were analysed both with the i-STAT and with in-house analysers to compare the values of pH, partial pressure of oxygen (PO2), partial pressure of carbon dioxide (PCO2), bicarbonate (HCO3), lactate and base excess (BE). The i-STAT demonstrated acceptable accuracy and precision for determination of pH, PO2 and PCO2, and lactate. We concluded that these parameters could be reliably evaluated by the i-STAT. The i-STAT was further evaluated at veterinary checkpoints during a 60 and 100 mile endurance ride. Because a built-in thermostat prevents function when the temperature of the analyser is outside the optimum range (16-30 degrees C), it was necessary to insulate the i-STAT from extreme ambient temperatures. As this portion of the study was conducted in warm temperatures, the appropriate insulation was to maintain the i-STAT in an ice-cooled container except during actual blood analyses. Further investigation into the feasibility of using hand-held chemical analysers at the veterinary checkpoints during endurance rides is recommended.
Authors:
S C Silverman; E K Birks
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Equine veterinary journal. Supplement     Volume:  -     ISSN:  -     ISO Abbreviation:  Equine Vet J Suppl     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-10-30     Completed Date:  2003-02-26     Revised Date:  2007-05-18    
Medline Journal Info:
Nlm Unique ID:  9614088     Medline TA:  Equine Vet J Suppl     Country:  England    
Other Details:
Languages:  eng     Pagination:  551-4     Citation Subset:  IM    
Affiliation:
Department of Clinical Studies, University of Pennsylvania, Kennett Square 19348, USA.
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MeSH Terms
Descriptor/Qualifier:
Acid-Base Equilibrium
Animals
Bicarbonates / blood
Blood Gas Analysis / instrumentation,  methods,  veterinary*
Carbon Dioxide / blood
Exercise Test / veterinary
Horses / blood*,  physiology
Hydrogen-Ion Concentration
Lactates / blood
Male
Oxygen / blood
Oxygen Consumption
Partial Pressure
Physical Conditioning, Animal / physiology*
Physical Endurance / physiology*
Point-of-Care Systems
Reproducibility of Results
Sensitivity and Specificity
Chemical
Reg. No./Substance:
0/Bicarbonates; 0/Lactates; 124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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