| Evaluation of the Roche Cobas Argos 5Diff automated haematology analyser with comparison to a Coulter STKS. | |
| | |
MedLine Citation:
|
PMID: 7955920 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The performance of the Roche Cobas Argos 5Diff (Argos) automated haematology analyser was evaluated by comparison to manual blood film examination and a Coulter STKS (STKS) analyser. The Argos demonstrated excellent between and inter-batch imprecision for all parameters, except the MCHC, and good linearity for Hb, WBC and platelet count (PLT). After an initial fall the PLT, results were stable for up to six h at 18 degrees C in EDTA(K3) after which an increasing proportion of cells were classified as lymphocytes. Results of 239 patient samples analysed on both instruments, compared by linear regression, gave excellent correlation (r2 > 0.90) for most parameters with the exceptions of the MCHC (0.317), eosinophils% (0.756), monocytes% (0.48) and basophils% (0.002). 'Flagging' of cellular abnormalities by the Argos resulted in excellent sensitivity (97.5%), specificity (93.2%) and efficiency/agreement (93.2%), with fewer false positive and negative results than the STKS, although these differences were not statistically significant. The performance characteristics of the Argos were comparable to those of the STKS with a possible improvement in its flagging abilities. |
| | |
Authors:
|
B L Sheridan; M Lollo; S Howe; N Bergeron |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Clinical and laboratory haematology Volume: 16 ISSN: 0141-9854 ISO Abbreviation: Clin Lab Haematol Publication Date: 1994 Jun |
Date Detail:
|
Created Date: 1994-12-06 Completed Date: 1994-12-06 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7907061 Medline TA: Clin Lab Haematol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 117-30 Citation Subset: IM |
Affiliation:
|
Department of Laboratory Haematology, Sunnybrook Health Science Centre, Toronto, Ontario, Canada. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Autoanalysis
/
instrumentation Blood Cell Count / instrumentation* Blood Preservation Evaluation Studies as Topic Humans Linear Models Predictive Value of Tests Reproducibility of Results Sensitivity and Specificity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Stable strontium absorption as a measure of intestinal calcium absorption: comparison with the doubl...
Next Document: Primary thrombocythaemia: a composite approach to diagnosis.