| Evaluation of Plasmodium vivax ELISA for the blood screen. | |
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MedLine Citation:
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PMID: 20955372 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Plasmodium vivax malaria is the indigenous strain in the Republic of Korea (ROK). Plasmodium vivax can be transmitted through the transfusions of various blood components, which became a severe problem with the safety of blood transfusions and blood-related products in ROK. We evaluated a P. vivax-specific enzyme-linked immunosorbent assay (Genedia Malaria Ab ELISA 2.0, Green Cross, ROK) with blood samples from four groups: 251 samples from P. vivax-infected patients, 39 samples from post-treatment patients upon follow-up, 200 samples from healthy volunteers and 421 samples from domestic travellers to and from high endemic areas of ROK. The positive cases from the ELISA test were confirmed by both Giemsa microscopic and polymerase chain reaction methods. The clinical sensitivity and specificity of detecting P. vivax with ELISA test were 94.4% and 99.0%, respectively. Thirteen of 421 domestic travellers (3.0%) to endemic areas tested positive. The results indicate the effectiveness of detecting antibodies against P. vivax in blood with Genedia Malaria Ab ELISA 2.0 test in a large blood screen setting. |
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Authors:
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Myung-Hyun Nam; Jang Su Kim; Chi Hyun Cho; Eun Taek Han; Won Ja Lee; Hee Kyung Lee; Seong Soo A An; Chae Seung Lim; Kap No Lee |
Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-10-18 |
Journal Detail:
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Title: Tropical medicine & international health : TM & IH Volume: 15 ISSN: 1365-3156 ISO Abbreviation: Trop. Med. Int. Health Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-22 Completed Date: 2010-12-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610576 Medline TA: Trop Med Int Health Country: England |
Other Details:
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Languages: eng Pagination: 1436-41 Citation Subset: IM |
Copyright Information:
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© 2010 Blackwell Publishing Ltd. |
Affiliation:
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Department of Laboratory Medicine, College of Medicine, Korea University, Seoul, Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Protozoan
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blood* Blood Donors* Blood-Borne Pathogens / isolation & purification Endemic Diseases Enzyme-Linked Immunosorbent Assay / methods Humans Malaria, Vivax / diagnosis*, epidemiology, transmission Mass Screening / methods Parasitemia / diagnosis Plasmodium vivax / immunology* Republic of Korea / epidemiology Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Protozoan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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