Document Detail

Evaluation of the PhysioFlex closed-circuit anaesthesia machine.
MedLine Citation:
PMID:  10928435     Owner:  NLM     Status:  MEDLINE    
The concentrations of nitrous oxide, sevoflurane and oxygen in the circle system of a closed-circuit anaesthesia machine, the PhysioFlex, were measured in seven patients. During anaesthesia, the settings for each gas were changed and their concentrations recorded. At the induction of anaesthesia, it took 80-510s (median 190s) for the end-tidal sevoflurane concentration to reach 2.0%, and 920-2640s (median 1500s) for the oxygen in the breathing circuit to reach 30%. At this time, the nitrous oxide concentration was 60+/-3% (mean+/-SD). During anaesthesia, it took 90-480s (median 140s) for the end-tidal sevoflurane concentration setting to decrease from 3.0 to 1.0%, and 90-400s (median 110s) to return from 1.0 to 3.0%. When the inspired oxygen was increased from 30 to 50%, circuit concentrations reached equilibrium in 40-60s (median 40s), and when decreased from 50% back to 30%, equilibrium took 310-470s (median 450s). During recovery from anaesthesia, inspiratory sevoflurane concentration took 40-70s (median 50s) to decrease to 0.2%. The PhysioFlex provided adequate control of sevoflurane and oxygen concentrations, but not of increasing nitrous oxide concentrations.
A Suzuki; H Bito; Y Sanjo; T Katoh; S Sato
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Publication Detail:
Type:  Clinical Trial; Evaluation Studies; Journal Article    
Journal Detail:
Title:  European journal of anaesthesiology     Volume:  17     ISSN:  0265-0215     ISO Abbreviation:  Eur J Anaesthesiol     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-11-30     Completed Date:  2000-11-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8411711     Medline TA:  Eur J Anaesthesiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  359-63     Citation Subset:  IM    
Department of Anesthesiology and Intensive Care, Hamamatsu University School of Medicine, Japan.
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MeSH Terms
Anesthesia, Closed-Circuit / instrumentation*
Anesthetics, Inhalation
Methyl Ethers
Middle Aged
Nitrous Oxide
Oxygen Inhalation Therapy
Respiratory Function Tests
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Methyl Ethers; 10024-97-2/Nitrous Oxide; 28523-86-6/sevoflurane

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