Document Detail

Evaluation of noncontact mapping by comparison with simultaneous multisite contact recordings in acute ischemic ventricular fibrillation.
MedLine Citation:
PMID:  20840465     Owner:  NLM     Status:  In-Data-Review    
Noncontact Mapping in Acute Ischemic VF. Aim: The study aim was to determine the utility of noncontact mapping in acute ischemic ventricular fibrillation, by direct comparison with simultaneously acquired multisite contact needle recordings. Materials and Methods: Noncontact mapping has emerged as a promising tool to make percutaneous high-density intracardiac electrical recordings in clinical and research settings. Previous large-animal mapping studies of ischemic VF have used electrodes in contact with the fibrillating myocardium. A previous report of noncontact mapping in VF used a single intracardiac catheter to validate noncontact recordings. Results: We studied the spontaneous onset of VF in 8 sheep, after acute occlusion of the left anterior descending coronary artery. Simultaneous unipolar recordings of endocardial electrical activation were made with the most endocardial electrode of 32 transmural plunge needles (contact electrograms; CE), and an Ensite noncontact catheter in the left ventricle (noncontact virtual electrograms; NCVE). The lag-shifted morphology cross-correlation between individual NCVE and CE pairs during VF was calculated. Discussion: The mean lag-shifted cross-correlation coefficient during manually selected sinus rhythm beats was 0.89 ± 0.006, and 0.80 ± 0.009 in VF (P < 0.05). The mean absolute time shift was 7.3 ± 0.5 ms in sinus rhythm, and 23.8 ± 0.9 ms in VF (P < 0.001). Fast Fourier transform demonstrated well-correlated dominant frequencies between CE and NCVE. VF myocardial activation maps of NCVE showed organized wavefronts, but dyssynchronous activation in CE. Conclusion: These data demonstrate errors in activation timing and sequence with noncontact mapping more prominent during VF than sinus rhythm. (J Cardiovasc Electrophysiol, Vol. 22, pp. 334-339, March 2011).
Anand N Ganesan; Gary Wu; Kevin Liou; Jim Pouliopoulos; Michael A Barry; Stuart P Thomas
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Publication Detail:
Type:  Journal Article     Date:  2010-09-14
Journal Detail:
Title:  Journal of cardiovascular electrophysiology     Volume:  22     ISSN:  1540-8167     ISO Abbreviation:  J. Cardiovasc. Electrophysiol.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9010756     Medline TA:  J Cardiovasc Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  334-9     Citation Subset:  IM    
Copyright Information:
© 2010 Wiley Periodicals, Inc.
Department of Cardiology, Westmead Hospital, Sydney, Australia Faculty of Medicine, University of Sydney, Australia.
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