| Evaluation of Cytotoxicity and Physicochemical Properties of Calcium Silicate-based Endodontic Sealer MTA Fillapex. | |
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MedLine Citation:
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PMID: 23321245 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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INTRODUCTION: The aim of the study was to evaluate the cytotoxicity, radiopacity, pH, and flow of a calcium silicate-based and an epoxy resin-based endodontic sealer, MTA Fillapex (Angelus, Londrina, PR, Brazil) and AH Plus (Dentsply, Konstanz, Germany), respectively. METHODS: Cytotoxicity, radiopacity, and flow evaluation were performed following ISO requirements. The pH level was measured at periods of 3, 24, 72, and 168 hours. Cytotoxicity was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay to check the Balb/c 3T3 cells viability at 1- to 4-week periods. Data were statistically analyzed by analysis of variance and the Tukey test with a significance level of 5%. RESULTS: In all tested periods, MTA Fillapex was more cytotoxic than AH Plus (P < .05). Although AH Plus presented higher radiopacity than MTA Fillapex (P < .05), both sealers showed minimum required values. MTA Fillapex presented alkaline pH in all experimental times, whereas AH Plus cement showed a slightly neutral pH and a flow significantly lower than that of MTA Fillapex (P < .05). CONCLUSIONS: Although MTA Fillapex was more cytotoxic than AH Plus, it showed suitable physicochemical properties for an endodontic sealer. |
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Authors:
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Emmanuel J N L Silva; Tiago P Rosa; Daniel R Herrera; Rogério C Jacinto; Brenda P F A Gomes; Alexandre A Zaia |
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Publication Detail:
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Type: Journal Article Date: 2012-08-09 |
Journal Detail:
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Title: Journal of endodontics Volume: 39 ISSN: 1878-3554 ISO Abbreviation: J Endod Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-01-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7511484 Medline TA: J Endod Country: United States |
Other Details:
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Languages: eng Pagination: 274-7 Citation Subset: D |
Copyright Information:
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Copyright © 2013 American Association of Endodontists. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Restorative Dentistry, Endodontics Division, Piracicaba Dental School, State University of Campinas, Piracicaba, Sao Paulo, Brazil. Electronic address: nogueiraemmanuel@hotmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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