| Evaluation of Antifungal Effects of a Traditional Medicine Containing 17 Components on Trichophyton verrucosum and Malassezia pachydermatis by Microdilution. | |
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MedLine Citation:
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PMID: 21891983 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The minimum inhibitory concentration(MIC)of a traditional medicine containing 17 components against 9 strains of Trichophyton verrucosum and 13 strains of Malassezia pachydermatis was determined using a method recommended by the Clinical and Laboratory Standards Institute(CLSI). We also measured the MIC of each of the 17 components using the same method, and identified the main antifungal components.In order to evaluate MIC as a parameter of the antifungal effects using the microdilution method, we prepared 10% working solutions from 10%(w/v)medicines. The geometric mean MIC of the medicinal extract against T. verrucosum was 2.51 %, and that against M. pachydermatis was 2.25%. The components that exhibited antifungal effects were Rheum palmatum, Glycyrrhiza uralensis, Magnolia obovata, Phellodendron amurense, and Geranium thunbergii. |
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Authors:
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Naoko Nishikata; Kentaro Nakamori; Masuo Sueyoshi; Hideo Takahashi; Hiroyuki Yuji; Ayako Sano |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Medical mycology journal Volume: 52 ISSN: 1882-0476 ISO Abbreviation: Med Mycol J Publication Date: 2011 |
Date Detail:
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Created Date: 2011-09-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101562838 Medline TA: Med Mycol J Country: Japan |
Other Details:
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Languages: eng Pagination: 213-21 Citation Subset: IM |
Affiliation:
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Miyazaki Prefectural Industrial Support Foundation. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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