Document Detail

Evaluation of Antifungal Effects of a Traditional Medicine Containing 17 Components on Trichophyton verrucosum and Malassezia pachydermatis by Microdilution.
MedLine Citation:
PMID:  21891983     Owner:  NLM     Status:  In-Data-Review    
The minimum inhibitory concentration(MIC)of a traditional medicine containing 17 components against 9 strains of Trichophyton verrucosum and 13 strains of Malassezia pachydermatis was determined using a method recommended by the Clinical and Laboratory Standards Institute(CLSI). We also measured the MIC of each of the 17 components using the same method, and identified the main antifungal components.In order to evaluate MIC as a parameter of the antifungal effects using the microdilution method, we prepared 10% working solutions from 10%(w/v)medicines. The geometric mean MIC of the medicinal extract against T. verrucosum was 2.51 %, and that against M. pachydermatis was 2.25%. The components that exhibited antifungal effects were Rheum palmatum, Glycyrrhiza uralensis, Magnolia obovata, Phellodendron amurense, and Geranium thunbergii.
Naoko Nishikata; Kentaro Nakamori; Masuo Sueyoshi; Hideo Takahashi; Hiroyuki Yuji; Ayako Sano
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical mycology journal     Volume:  52     ISSN:  1882-0476     ISO Abbreviation:  Med Mycol J     Publication Date:  2011  
Date Detail:
Created Date:  2011-09-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101562838     Medline TA:  Med Mycol J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  213-21     Citation Subset:  IM    
Miyazaki Prefectural Industrial Support Foundation.
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