| Evaluating tumors in transcatheter arterial chemoembolization (TACE) using dual-phase cone-beam CT. | |
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MedLine Citation:
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PMID: 21082901 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Abstract C-arm cone-beam computed tomography (CBCT) can be used to visualize tumor-feeding vessels and parenchymal staining during transcatheter arterial chemoembolization (TACE). To capture these two phases, all current commercially available CBCT systems necessitate two separate contrast-enhanced scans. In this feasibility study, we report initial results of novel software that enhanced our current CBCT system to capture these two phases using only one contrast injection. Novelty of this work is the addition of software that enabled the acquisition of two sequential, back-to-back CBCT scans (dual-phase CBCT, DPCBCT) so both tumor feeding vessels and parenchyma are captured using only one contrast injection. To illustrate our initial experience, DPCBCT was used for TACE treatments involving lipiodol, drug-eluting beads, and Yttrium-90 radioembolizing microspheres. For each case, the DPCBCT images were compared to pre-intervention contrast-enhanced MR/CT. DPCBCT is feasible for TACE treatments and the preliminary results show positive correlation with pre-intervention conventional CT and MR. In addition, the degree of embolization can be monitored. DPCBCT is a promising technology that provides comprehensive visualization of tumor-feeding vessels and parenchymal staining using a single injection of contrast. DPCBCT could potentially be used during TACE to verify catheter position and monitor the embolization effect. |
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Authors:
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Mingde Lin; Romaric Loffroy; Niels Noordhoek; Katsuyuki Taguchi; Alessandro Radaelli; Järl Blijd; Angelique Balguid; Jean-François Geschwind |
Publication Detail:
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Type: Journal Article Date: 2010-11-17 |
Journal Detail:
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Title: Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy Volume: 20 ISSN: 1365-2931 ISO Abbreviation: Minim Invasive Ther Allied Technol Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-10-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9612996 Medline TA: Minim Invasive Ther Allied Technol Country: England |
Other Details:
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Languages: eng Pagination: 276-81 Citation Subset: IM |
Affiliation:
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Philips Research North America, Briarcliff Manor, NY , USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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