Document Detail


Evaluating an optimal gastric closure method for transgastric surgery.
MedLine Citation:
PMID:  17160493     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The transgastric approach is currently being studied as a potentially less invasive alternative to conventional laparoscopy for intra-abdominal surgery. A major obstacle to overcome is the closure of the transgastric incision in a rapid, reproducible, and safe manner. The effectiveness of various techniques for gastrotomy closure were compared by assessing leak pressures in an ex vivo porcine stomach model. METHODS: Whole stomachs from adult white pigs were suspended in a Plexiglas box to facilitate endoscopic technique. Standard gastrotomies were made by needle knife incision and dilation with a controlled radial expansion (CRE) balloon. The first arm used standard QuickClips; the second, a prototype device developed by LSI Solutions; the third, hand-sewn by a senior surgeon; the final, a control with open gastrotomy. Five stomachs were tested per study arm. After closure, each stomach was inflated by an automated pressure gauge. The pressures to achieve air leakage and liquid leakage were recorded. RESULTS: The unclosed controls demonstrated air leakage at a median pressure of 15 mmHg, representing baseline system resistance. The QuickClip closures leaked air at a median pressure of 33 mmHg. The prototype gastrotomy device yielded the highest median air leak pressure of 85 mmHg while dramatically diminishing time for incision and gastrotomy closure to approximately 5 min. The hand-sewn closures leaked air at a median pressure of 47 mmHg. Using Kruskal-Wallis statistical analysis, the comparisons were significant (p = 0.0019). Post hoc paired comparisons using MULTTEST procedure with both Bonferroni and bootstrap adjustments revealed that the difference between prototype and clips was significant; prototype versus hand-sewn was not. Liquid-leak pressures produced similar results. CONCLUSIONS: The prototype device decreases procedure time and yields leak-resistant gastrotomy closures that are superior to clips and rival hand-sewn interrupted stitches.
Authors:
M Ryou; R D Pai; R Pai; J S Sauer; J Sauer; D W Rattner; D Rattner; C C Thompson; C Thompson
Related Documents :
20634793 - A prospective study of the accuracy and precision of continuous cardiac output monitori...
15788933 - Measuring blood pressure using the mercury sphygmomanometer.
9869993 - Review article: heart rate and blood pressure control in vasovagal syncope.
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2006-12-08
Journal Detail:
Title:  Surgical endoscopy     Volume:  21     ISSN:  1432-2218     ISO Abbreviation:  Surg Endosc     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-16     Completed Date:  2007-04-12     Revised Date:  2007-09-10    
Medline Journal Info:
Nlm Unique ID:  8806653     Medline TA:  Surg Endosc     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  677-80     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, Brigham & Women's Hospital, 75 Francis St., Boston, Massachusetts 02115, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Disease Models, Animal
Endoscopy, Gastrointestinal / methods*
Equipment Design
Equipment Safety
Gastroenterostomy / methods*
Gastroscopy / methods*
Pressure
Random Allocation
Reference Values
Sensitivity and Specificity
Suture Techniques / instrumentation*
Swine
Tensile Strength
Comments/Corrections
Erratum In:
Surg Endosc. 2007 Aug;21(8):1472
Note: Pai, R [corrected to Pai, RD]; Sauer, J [corrected to Sauer, JS]; Rattner, D [corrected to Rattner, DW]; Thompson, C [corrected to Thompson, CC]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Animal health problems attributed to environmental contamination in lake Nakuru National Park, Kenya...
Next Document:  Cellular, hemostatic, and inflammatory parameters of the surgical stress response in pigs undergoing...