Document Detail

Evaluating the mitochondrial timescale of human evolution.
MedLine Citation:
PMID:  19682765     Owner:  NLM     Status:  MEDLINE    
Different methodologies and modes of calibration have produced disparate, sometimes irreconcilable, reconstructions of the evolutionary and demographic history of our species. We discuss how date estimates are affected by the choice of molecular data and methodology, and evaluate various mitochondrial estimates of the timescale of human evolution in the context of the contemporary palaeontological and archaeological evidence for key stages in human prehistory. We contend that some of the most widely-cited mitochondrial rate estimates have several significant shortcomings, including a reliance on a human-chimpanzee calibration, and highlight the pressing need for revised rate estimates.
Phillip Endicott; Simon Y W Ho; Mait Metspalu; Chris Stringer
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-08-12
Journal Detail:
Title:  Trends in ecology & evolution     Volume:  24     ISSN:  0169-5347     ISO Abbreviation:  Trends Ecol. Evol. (Amst.)     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-25     Completed Date:  2009-10-23     Revised Date:  2011-05-03    
Medline Journal Info:
Nlm Unique ID:  8805125     Medline TA:  Trends Ecol Evol     Country:  England    
Other Details:
Languages:  eng     Pagination:  515-21     Citation Subset:  IM    
Départment Hommes Natures Sociétés, Musée de l'Homme, Paris, France.
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MeSH Terms
Biological Evolution*
DNA, Mitochondrial / chemistry
Evolution, Molecular
Genome, Mitochondrial
Mitochondria / genetics*
Time Factors
Reg. No./Substance:
0/DNA, Mitochondrial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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