Document Detail


Evaluating functional decline in patients with Multiple Sclerosis.
MedLine Citation:
PMID:  20047816     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Multiple Sclerosis (MS) is a disease with a wide-ranging impact on functional status. The aim of the study was to examine the added value of simultaneously evaluating fatigue, personal ADL and handwriting performance as indicators for functional decline among patients with MS. Participants were 50 outpatients with MS and 26 matched healthy controls. Data collection instruments included a disability status scale, the Fatigue Severity Scale (FSS), and the Physical Self-Maintenance Scale (PSMS). Handwriting performance was evaluated by objective computerized measures of the handwriting process (ComPET). Significant differences were found between patients with MS and control subjects in their fatigue level, their PSMS score and In-air time per stroke while writing. The FSS together with specific PSMS items and handwriting measures achieved correct classification of 87.7% of the participants. These results are the first step towards demonstrating the added value of evaluating body function outcomes (fatigue) together with activity performance (handwriting and ADL) to document functional decline among patients with MS. These results may contribute to the development of practical intervention strategies targeted at improving performance abilities among patients with MS.
Authors:
Sara Rosenblum; Patrice L Tamar Weiss
Related Documents :
7674346 - Immunomodulation in the treatment of multiple sclerosis and amyotrophic lateral scleros...
8340796 - Brain magnetic resonance imaging correlates of cognitive impairment in multiple sclerosis.
3900686 - Electrophysiologic evaluation of patients with multiple sclerosis.
20050906 - Neutralizing antibodies, mxa expression and mmp-9/timp-1 ratio as markers of bioavailab...
6316866 - Normal cortisol response to corticotropin in patients with secondary adrenal failure.
22477576 - Unusual presentation of mönckeberg's sclerosis in the thyroid vessels of three female ...
Publication Detail:
Type:  Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-01-04
Journal Detail:
Title:  Research in developmental disabilities     Volume:  31     ISSN:  1873-3379     ISO Abbreviation:  Res Dev Disabil     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-02-22     Completed Date:  2010-05-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8709782     Medline TA:  Res Dev Disabil     Country:  United States    
Other Details:
Languages:  eng     Pagination:  577-86     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Occupational Therapy, Faculty of Social Welfare & Health Sciences, University of Haifa, Haifa, Israel. rosens@research.haifa.ac.il
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Activities of Daily Living
Adolescent
Adult
Aged
Disability Evaluation*
Fatigue / diagnosis,  physiopathology
Female
Handwriting
Humans
Male
Middle Aged
Multiple Sclerosis, Chronic Progressive / diagnosis*,  physiopathology*
Multiple Sclerosis, Relapsing-Remitting / diagnosis*,  physiopathology*
Outpatients
Recurrence
Self Care
Severity of Illness Index
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The application of fully automated on-line solid phase extraction in bioanalysis.
Next Document:  Surgical challenges in the treatment of advanced cases of ameloblastoma in the developing world: The...