Document Detail

Evaluating elements of executive functioning as predictors of instrumental activities of daily living (IADLs).
MedLine Citation:
PMID:  16814980     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Executive functioning has been repeatedly linked to the integrity of instrumental activities of daily living (IADL). The present study examined the association of multiple executive functioning elements (i.e., working memory, generation, inhibition, planning, and sequencing) to IADLs among an older adult cohort at risk for future cognitive and functional decline.
METHODS: Seventy-two participants with prevalent but stable cardiovascular disease completed a neuropsychological protocol assessing multiple elements of executive functioning, including COWA, PASAT, DKEFS Color-Word Interference Test, DKEFS Trail-Making Test, DKEFS Tower Test, and Ruff Figural Fluency Test. Reliable informants completed a measure of IADLs.
RESULTS: Stepwise logistic regression selected a model involving a single significant predictor, a measure of inhibition (i.e., DKEFS Color-Word Interference Test), which had a significant regression coefficient. Subsequent correlation analyses confirmed an association between the inhibition measure and multiple IADL items. Inter-item comparisons among the IADLs revealed significant differences, such that telephone use and laundry were significantly more intact than most other IADLs while shopping and housekeeping were most compromised.
CONCLUSIONS: Our data suggest that inhibition, also known as susceptibility to interference, is most strongly related to IADL impairment among patients at risk for future cognitive and functional decline.
Angela L Jefferson; Robert H Paul; Al Ozonoff; Ronald A Cohen
Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists     Volume:  21     ISSN:  0887-6177     ISO Abbreviation:  Arch Clin Neuropsychol     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-07-12     Completed Date:  2006-09-05     Revised Date:  2014-09-05    
Medline Journal Info:
Nlm Unique ID:  9004255     Medline TA:  Arch Clin Neuropsychol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  311-20     Citation Subset:  IM    
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MeSH Terms
Activities of Daily Living*
Cardiovascular Diseases / physiopathology
Disability Evaluation
Geriatric Assessment
Inhibition (Psychology)
Logistic Models
Memory, Short-Term / physiology*
Mental Status Schedule / statistics & numerical data
Middle Aged
Neuropsychological Tests / statistics & numerical data*
Predictive Value of Tests
Problem Solving / physiology*
Residence Characteristics
Sampling Studies
Grant Support
AG013846/AG/NIA NIH HHS; AG017975/AG/NIA NIH HHS; AG022773/AG/NIA NIH HHS; F32 AG022773/AG/NIA NIH HHS; F32 AG022773-01/AG/NIA NIH HHS; F32 AG022773-02/AG/NIA NIH HHS; HD043444/HD/NICHD NIH HHS; MH065857/MH/NIMH NIH HHS; P30 AG013846/AG/NIA NIH HHS; P30 AG013846-06/AG/NIA NIH HHS

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