Document Detail

Evaluating the efficacy of treatment of resistant port-wine stains with variable-pulse 595-nm pulsed dye and 532-nm Nd:YAG lasers.
MedLine Citation:
PMID:  14756643     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Some port wine stains (PWSs), despite multiple treatments with the 585-nm 0.45-ms pulsed dye laser (PDL), fail to improve substantially. OBJECTIVE: To determine the efficacy and tolerability of variable pulse width 595-nm PDL and 532-nm Nd:YAG laser in the treatment of resistant PWS. METHODS: Twenty-two patients whose PWS failed to achieve more than 75% lightening after more than 15 treatments with the 585-nm 0.45-ms PDL were recruited. A homogenous patch of PWS was divided into five areas. Area 1 (control area) was treated with 585-nm, 0.45-ms PDL (fluence 7.5 J/cm2). Areas 2 and 3 were treated with 595-nm PDL at fluence 15 J/cm2 (with cryogen spray cooling) and pulse durations of 1.5 and 10 ms, respectively. Areas 4 and 5 were treated with a 532-nm Nd:YAG laser at 2 ms, 7 J/cm2 and 10 ms, 16 J/cm2, respectively (with a contact cooling tip). The response was assessed by photographic evaluation. RESULTS: Three patients had further lightening in area 2, and two patients had further lightening in area 3. Each of three patients had further lightening in areas 4 and 5, respectively. One patient had further lightening in the control area. CONCLUSION: In individual patients, it may be effective to treat resistant PWS with the variable-pulse width 595-nm PDL and the 532-nm Nd:YAG laser.
Wai Kit Woo; Zaid F Jasim; Julian M Handley
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  30     ISSN:  1076-0512     ISO Abbreviation:  Dermatol Surg     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-02-03     Completed Date:  2004-04-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  158-62; discussion 162     Citation Subset:  IM    
Department of Dermatology, Ulster Hospital, Belfast, United Kingdom.
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MeSH Terms
Laser Therapy, Low-Level / methods*
Middle Aged
Port-Wine Stain / radiotherapy*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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