| European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease. | |
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MedLine Citation:
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PMID: 2209656 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201Tl) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for 201T1 and 96% for 99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study 99mTc-MIBI was as accurate as 201Tl for the detection of coronary artery stenoses. |
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Authors:
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M N Maisey; A Lowry; A Bischof-Delaloye; R Fridrich; E Inglese; M N Khalil; J B van der Schoot |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Multicenter Study |
Journal Detail:
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Title: European journal of nuclear medicine Volume: 16 ISSN: 0340-6997 ISO Abbreviation: Eur J Nucl Med Publication Date: 1990 |
Date Detail:
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Created Date: 1990-11-19 Completed Date: 1990-11-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7606882 Medline TA: Eur J Nucl Med Country: GERMANY |
Other Details:
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Languages: eng Pagination: 869-72 Citation Subset: IM |
Affiliation:
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Division of Radiological Sciences, UMDS, Guy's Hospital, London Bridge, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Contrast Media Coronary Disease / radionuclide imaging* Europe Female Heart / radionuclide imaging* Humans Male Middle Aged Nitriles / diagnostic use* Organotechnetium Compounds / diagnostic use* Sensitivity and Specificity Technetium Tc 99m Sestamibi Thallium Radioisotopes / diagnostic use* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Nitriles; 0/Organotechnetium Compounds; 0/Thallium Radioisotopes; 109581-73-9/Technetium Tc 99m Sestamibi |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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