Document Detail

European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease.
MedLine Citation:
PMID:  2209656     Owner:  NLM     Status:  MEDLINE    
Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201Tl) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for 201T1 and 96% for 99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study 99mTc-MIBI was as accurate as 201Tl for the detection of coronary artery stenoses.
M N Maisey; A Lowry; A Bischof-Delaloye; R Fridrich; E Inglese; M N Khalil; J B van der Schoot
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Multicenter Study    
Journal Detail:
Title:  European journal of nuclear medicine     Volume:  16     ISSN:  0340-6997     ISO Abbreviation:  Eur J Nucl Med     Publication Date:  1990  
Date Detail:
Created Date:  1990-11-19     Completed Date:  1990-11-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7606882     Medline TA:  Eur J Nucl Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  869-72     Citation Subset:  IM    
Division of Radiological Sciences, UMDS, Guy's Hospital, London Bridge, UK.
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MeSH Terms
Contrast Media
Coronary Disease / radionuclide imaging*
Heart / radionuclide imaging*
Middle Aged
Nitriles / diagnostic use*
Organotechnetium Compounds / diagnostic use*
Sensitivity and Specificity
Technetium Tc 99m Sestamibi
Thallium Radioisotopes / diagnostic use*
Reg. No./Substance:
0/Contrast Media; 0/Nitriles; 0/Organotechnetium Compounds; 0/Thallium Radioisotopes; 109581-73-9/Technetium Tc 99m Sestamibi

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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