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Eumycetoma versus actinomycetoma: Diagnosis on cytology.
MedLine Citation:
PMID:  21157564     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Eumycetoma is a chronic cutaneous and subcutaneous infection caused by various genera of fungi producing specific colored granules known as grains. A 45-year-old farmer presented clinically with a left foot mass with multiple discharging sinuses existing for last 3 years. Clinical and radiological findings suggested a diagnosis of chronic osteomyelitis with suspicion of tuberculosis. Imprints plus fine needle aspiration cytology (FNAC) smears exhibited distinct brown-black colonies of a fungus having branching and septate hyphae embedded in matrix like material against a mixed inflammatory background. Periodic acid Schiff (PAS) stain gave positive staining and subsequent fungal culture confirmed the cytological diagnosis and aided in species identification as Madurella mycetomatis. Thus, eumycetoma can precisely be diagnosed and confidently differentiated from similar conditions such as actinomycetoma by simple and inexpensive cytological techniques such as FNAC and imprint smears, employing routine May-Grünwald-Giemsa, Papanicolaou and simple PAS stains on cytological specimen, thus leading to rapid diagnosis for institution of correct treatment.
Nishat Afroz; Nazoora Khan; Farhan A Siddiqui; Mehar Rizvi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cytology / Indian Academy of Cytologists     Volume:  27     ISSN:  0974-5165     ISO Abbreviation:  J Cytol     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-12-15     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  8915204     Medline TA:  J Cytol     Country:  India    
Other Details:
Languages:  eng     Pagination:  133-5     Citation Subset:  -    
Department of Pathology, J N Medical College, AMU Aligarh, India.
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