Document Detail


Etomidate: applications in pediatric critical care and pediatric anesthesiology.
MedLine Citation:
PMID:  12813258     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Etomidate is a carboxylated, imidazole-containing intravenous anesthetic agent introduced into clinical anesthesia practice in 1972. Its distinctive features that make it useful as an anesthetic induction include a lack of adverse effects on hemodynamic function as well as beneficial effects on cerebral blood flow and intracranial pressure. Because of these properties, its major role in anesthetic practice has been for the induction of anesthesia in patients with diminished cardiovascular function. As opposed to the considerable reported clinical experience with etomidate in the adult population, there remains limited reported information concerning its use in pediatric patients. This article reviews the specific end-organ effects of etomidate, the reports concerning its use in pediatric patients, and its adverse effect profile.
Authors:
J D Tobias
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies     Volume:  1     ISSN:  1529-7535     ISO Abbreviation:  Pediatr Crit Care Med     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2003-06-18     Completed Date:  2003-11-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954653     Medline TA:  Pediatr Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  100-6     Citation Subset:  -    
Affiliation:
Departments of Child Health and Anesthesiology, The Division of Pediatric Critical Care/Pediatric Anesthesiology, The University of Missouri, Columbia, MO 65212, USA. Tobiasj@health.missouri.edu
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