Document Detail


Etiology and management of anemia in patients with heart failure: how much iron is missing?
MedLine Citation:
PMID:  18256566     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Anemia is common among patients with heart failure (HF) and has been associated with worse prognosis. To date, it is not well known whether correction of anemia in these patients can improve outcome. Proposed modalities for correction of anemia have been either administration of erythropoiesis-stimulating proteins, which appears plausible in patients with concomitant renal failure (so-called cardiorenal syndrome), or iron supplementation, which is particularly attractive in patients with no overt renal failure and chronic disease anemia with some degree of iron deficiency. This article reviews the rationale for anemia correction and the latest randomized clinical trial assessing clinical utility of erythropoiesis-stimulating proteins and/or iron supplementation through oral or intravenous administration in anemic HF patients.
Authors:
Luis Beck da Silva; Luis E Rohde; Nadine Clausell
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Congestive heart failure (Greenwich, Conn.)     Volume:  14     ISSN:  1527-5299     ISO Abbreviation:  Congest Heart Fail     Publication Date:    2008 Jan-Feb
Date Detail:
Created Date:  2008-02-07     Completed Date:  2008-05-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9714174     Medline TA:  Congest Heart Fail     Country:  United States    
Other Details:
Languages:  eng     Pagination:  25-30     Citation Subset:  IM    
Affiliation:
Heart Failure and Cardiac Transplantation Units, Divisions of Cardiology at the Hospital de Clínicas de Porto Alegre Federal University of Rio Grande do Sul, Medical School, Porto Alegre, Brazil. lbneto@hcpa.ufrgs.br
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MeSH Terms
Descriptor/Qualifier:
Anemia / drug therapy,  etiology*
Erythropoietin / therapeutic use
Heart Failure / complications*,  physiopathology
Humans
Iron Compounds / administration & dosage*,  therapeutic use
Prevalence
Risk Factors
Chemical
Reg. No./Substance:
0/Iron Compounds; 11096-26-7/Erythropoietin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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