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Etiology of isolated mitral regurgitation: a clinico-echocardiographic study.
MedLine Citation:
PMID:  8314269     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
One hundred and ninety two consecutive patients with isolated mitral regurgitation (MR) with an audible murmur were studied for determination of etiology. There were 95 males & 97 females (mean age 24.5 +/- 10.8 years; range 13 to 58 years) with 102 patients in NYHA classes I and II, 81 in class III and 9 in NYHA class IV. The etiological grouping was: rheumatic 74 (38.5%), probable rheumatic 28 (15%), mitral valve prolapse 26 (13.5%), dilated cardiomyopathy 15 (8%), infective endocarditis 12 (6%), isochaemic heart disease 10 (5%), miscellaneous group (including rupture chordae tendinae, aortoarteritis etc) 9 (4.5%) and patients with indeterminate etiology 18 (9.5%). Etiology could be determined in 174 out of 192 cases. The clinical methods combined with echocardiography were helpful in 79 cases while echocardiography alone could diagnose etiology in 89 cases. Clinical features alone gave the diagnosis in 6 patients. The findings of gross morphology of the surgically removed mitral valves in 30 patients of this study were similar to their pre-operative etiologic diagnosis based on clinical and echocardiographic features. These findings may be of value in planning treatment and prophylactic strategies in cases of isolated MR.
Authors:
R Kumar; N Sinha; R C Ahuja; R K Saran; S K Dwivedi; A Suri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian heart journal     Volume:  45     ISSN:  0019-4832     ISO Abbreviation:  Indian Heart J     Publication Date:    1993 May-Jun
Date Detail:
Created Date:  1994-03-18     Completed Date:  1994-03-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374675     Medline TA:  Indian Heart J     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  173-8     Citation Subset:  IM    
Affiliation:
Department of Cardiology, SGPGl and KGMC, Lucknow.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cardiomyopathy, Dilated / complications
Echocardiography, Doppler*
Endocarditis, Bacterial / complications
Female
Heart Murmurs / etiology
Humans
Male
Middle Aged
Mitral Valve / ultrasonography
Mitral Valve Insufficiency / etiology*,  ultrasonography*
Mitral Valve Prolapse / complications
Rheumatic Heart Disease / complications

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