Document Detail

Etiology and incidence of chronic ulcers in Blantyre, Malawi.
MedLine Citation:
PMID:  16911377     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Little information is available on the incidence and etiology of chronic ulcers in the tropics. Therefore, the incidence and etiology of chronic skin ulcers were assessed in out-patients at the Department of Dermatology and in in-patients at the Departments of Dermatology, Surgery, Medicine, and Pediatrics, Queen Elizabeth Central Hospital (QECH), Blantyre, Malawi. METHOD: In a 10-week study period, 44 patients (31 males, 70%) with chronic skin ulcers were diagnosed from 6292 patients seen by the departments involved. RESULTS: The mean age of patients with ulcers was 38 years (range, 9 months to 82 years). The most frequent cause of ulcers was bacterial infection (n=22), followed by malignancy (n=11) and trauma (n=7). CONCLUSION: In contrast with developed countries, venous and diabetic ulcers were uncommon. In addition to bacterial infections, a surprisingly large number of malignancies were found in this study. We speculate that human immunodeficiency virus (HIV) infection, which is seen with a high prevalence at QECH, is a contributing factor. Because of the large number of malignancies, we recommend early histopathologic investigation of chronic ulcers in this part of Africa.
Jim E Zeegelaar; Aimee C Stroïnk; Willemyn H Steketee; William R Faber; Allard C van der Wal; Isaac O O Komolafe; Charles Dzamalala; Cecilia Chibwana; Johannes F Wendte; Eduard E Zijlstra
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of dermatology     Volume:  45     ISSN:  0011-9059     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-16     Completed Date:  2007-01-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  933-6     Citation Subset:  IM    
Department of Dermatology, Academic Medical Centre, Amsterdam, The Netherlands, and Department of Microbiology, College of Medicine, Blantyre, Malawi.
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MeSH Terms
Aged, 80 and over
Child, Preschool
Chronic Disease
Malawi / epidemiology
Middle Aged
Pyoderma / diagnosis,  epidemiology,  microbiology
Skin Diseases, Bacterial / diagnosis,  epidemiology,  microbiology
Skin Ulcer / diagnosis,  epidemiology*,  etiology*,  microbiology

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