Document Detail

Etiological diagnosis of left ventricular dysfunction: computed tomography compared with coronary angiography and cardiac magnetic resonance.
MedLine Citation:
PMID:  22079180     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION AND OBJECTIVES: To evaluate the capability of multidetector computed tomography to diagnose the coronary etiology of left ventricular dysfunction compared with using invasive coronary angiography and magnetic resonance.
METHODS: Forty consecutive patients with left ventricular dysfunction of uncertain etiology underwent invasive coronary angiography and contrast magnetic resonance. All patients were evaluated with multidetector computed tomography including coronary calcium presence and score, noninvasive coronary angiography, and myocardial tissue assessment.
RESULTS: The sensitivity and specificity of the presence of coronary calcium to identify left ventricular dysfunction was 100% and 31%, respectively. If an Agatston calcium score of >100 is taken, specificity increases to 58% with sensitivity still 100%. Sensitivity and specificity for coronary angiography by multidetector computed tomography was 100% and 96%, respectively; for identifying necrosis in contrast acquisition it was 57% and 100%, respectively; and in late acquisition, 84% and 96%, respectively. To identify coronary ventricular dysfunction with necrosis, the sensitivity and specificity was 92% and 100%, respectively.
CONCLUSIONS: Of all the diagnostic tools available in multidetector computed tomography, coronary angiography is the most accurate in determining the coronary origin of left ventricular dysfunction. A combination of coronary angiography and myocardial tissue study after contrast allows a single test to obtain similar information compared with the combination of invasive coronary angiography and contrast magnetic resonance.
Jordi Estornell-Erill; Begoña Igual-Muñoz; Jose Vicente Monmeneu-Menadas; Carlos Soriano-Navarro; Alfonso Valle-Muñoz; Juan V Vilar-Herrero; Leandro Perez-Bosca; Rafael Paya-Serrano; Nieves Martinez-Alzamora; Francisco Ridocci-Soriano
Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-11-10
Journal Detail:
Title:  Revista española de cardiología (English ed.)     Volume:  65     ISSN:  1885-5857     ISO Abbreviation:  Rev Esp Cardiol (Engl Ed)     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-21     Completed Date:  2012-09-21     Revised Date:  2012-12-31    
Medline Journal Info:
Nlm Unique ID:  101587954     Medline TA:  Rev Esp Cardiol (Engl Ed)     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  517-24     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Sociedad Española de Cardiología. Published by Elsevier Espana. All rights reserved.
Unidad de Imagen Cardiaca, ERESA, Valencia, España.
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MeSH Terms
Aged, 80 and over
Calcinosis / complications*,  diagnosis
Coronary Angiography / methods
Coronary Artery Disease / complications*,  diagnosis
Magnetic Resonance Imaging
Middle Aged
Multidetector Computed Tomography / methods
Prospective Studies
Sensitivity and Specificity
Ventricular Dysfunction, Left / etiology*
Comment In:
Rev Esp Cardiol (Engl Ed). 2012 Jun;65(6):501-3   [PMID:  22551983 ]

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