Document Detail

Ethylenevinylalcohol copolymer (Onyx-18) used in endovascular treatment of vein of Galen malformation.
MedLine Citation:
PMID:  17701187     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Vein of Galen malformations (VGM) are rare congenital arteriovenous fistulas that usually present with heart failure in the neonate. Endovascular treatment options in the past have utilized coils, balloons, and acrylics.
CASE REPORT: We present, for the first time in the literature, a case of an infant with VGM treated initially with staged coil embolizations followed 1 year later by the transarterial and transvenous catheter based injection of Onyx-18 (ethylenevinylalcohol copolymer) in a single treatment session. The fistula was eliminated, and the infant's cardiopulmonary symptoms were improved.
Anand V Germanwala; Nirav A Vora; Ajith J Thomas; Tudor Jovin; Yakov Gologorsky; Michael B Horowitz
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-08-15
Journal Detail:
Title:  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery     Volume:  24     ISSN:  1433-0350     ISO Abbreviation:  Childs Nerv Syst     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-11-23     Completed Date:  2009-02-19     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  8503227     Medline TA:  Childs Nerv Syst     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  135-8     Citation Subset:  IM    
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
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MeSH Terms
Embolization, Therapeutic / methods*
Heart Failure / etiology,  therapy*
Infant, Newborn
Injections, Intra-Arterial
Injections, Intravenous
Polyvinyls / administration & dosage,  therapeutic use*
Treatment Outcome
Vein of Galen Malformations / complications,  diagnosis,  therapy*
Reg. No./Substance:
0/Polyvinyls; 25067-34-9/ethylene-vinyl alcohol copolymer

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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