Document Detail


Ethylene glycol poisoning.
MedLine Citation:
PMID:  17629645     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 40-year-old man was admitted to the emergency department after a suicide attempt. The patient was found at home unconscious, with an open bottle of antifreeze near him. The patient was in a coma on admission, but neurological examination excluded intracranial changes. Results of initial urine and serum toxicological screening tests were negative. Laboratory values indicated metabolic acidosis, leukocytosis, urinalysis revealed hematuria and unrecognized crystals. Osmolality and osmol gap were not determined on patient admission. Treatment with ethanol as an antidote and hemodialysis were started because of metabolic acidosis, anamnestic data and clinical status of the patient, and subsequently led to improvement of his condition. Further toxicological analyses of glycolic and oxalic acids in serum and urine samples were performed by ion-chromatography (IC) method and showed high values in spot urine and serum ultrafiltrate at admission, but during therapy the values progressively decreased. Treatment of poisoned patient for 3 weeks resulted in complete recovery.
Authors:
Mila Lovrić; Paula Granić; Mirjana Cubrilo-Turek; Zdenka Lalić; Jadranka Sertić
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-07-16
Journal Detail:
Title:  Forensic science international     Volume:  170     ISSN:  1872-6283     ISO Abbreviation:  Forensic Sci. Int.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-07-30     Completed Date:  2007-10-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902034     Medline TA:  Forensic Sci Int     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  213-5     Citation Subset:  IM    
Affiliation:
Clinical Institute of Laboratory Diagnosis, Zagreb University Hospital Center, Kispatićeva 12, Zagreb, Croatia. lovricm@kbc-zagreb.hr <lovricm@kbc-zagreb.hr>
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MeSH Terms
Descriptor/Qualifier:
Acidosis / chemically induced,  therapy
Adult
Antidotes / therapeutic use
Ethanol / therapeutic use
Ethylene Glycol / adverse effects,  poisoning*
Forensic Toxicology
Hematuria / chemically induced
Humans
Leukocytosis / chemically induced
Male
Poisoning / therapy
Renal Dialysis
Suicide, Attempted*
Chemical
Reg. No./Substance:
0/Antidotes; 107-21-1/Ethylene Glycol; 64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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