| Ethnicity and arterial stiffness in Brazil. | |
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MedLine Citation:
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PMID: 21183929 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The impact of increased central arterial stiffness as a predictor of morbidity and mortality, independently of other cardiovascular (CV) risk factors, has been established. The main aim of the present work was to investigate the association of ethnicity on arterial stiffness in different ethnic groups from the Brazilian population. METHODS: A total of 1,427 individuals from the general population were randomly selected from the Vitoria City metropolitan area and 588 Amerindians from a native community in Brazil. The ethnicity of the general population was classified by a standard questionnaire as Caucasian descent, African descent, or Mulattos (considered racially mixed subjects). Pulse wave velocity (PWV) was measured with a noninvasive automatic device (Complior, Colson; Garges les Gonesses, France). RESULTS: Hemodynamic data of PWV, systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean blood pressure (MBP) was higher in African descent individuals than in the other groups (P < 0.001). These results were still observed after adjustment for age and mean arterial pressure (P < 0.001). In addition, studying only normotensive individuals, PWV adjusted levels were higher in African descent individuals, and lower in Amerindians when compared with other ethnic groups (P < 0.01), showing, without the possible confounder effects of time and severity of hypertension or medication use, that PWV is associated with ethnicity in our population. CONCLUSION: The study of different ethnic groups from a highly admixtured population was able to demonstrate an association between ethnicity and arterial stiffness. |
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Authors:
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Paulo Caleb Júnior de Lima Santos; Rafael de Oliveira Alvim; Noely Evangelista Ferreira; Roberto de Sá Cunha; José Eduardo Krieger; José Geraldo Mill; Alexandre Costa Pereira |
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Publication Detail:
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Type: Journal Article Date: 2010-12-23 |
Journal Detail:
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Title: American journal of hypertension Volume: 24 ISSN: 1941-7225 ISO Abbreviation: Am. J. Hypertens. Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-15 Completed Date: 2011-06-15 Revised Date: 2011-06-30 |
Medline Journal Info:
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Nlm Unique ID: 8803676 Medline TA: Am J Hypertens Country: United States |
Other Details:
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Languages: eng Pagination: 278-84 Citation Subset: IM |
Affiliation:
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Laboratory of Genetics and Molecular Cardiology, Heart Institute, University of Sao Paulo Medical School, Brazil. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Flow Velocity / physiology* Blood Pressure Brazil / ethnology Cardiovascular Diseases / etiology Carotid Arteries / physiopathology* Cross-Sectional Studies Elasticity Female Femoral Artery / physiopathology* Humans Male Middle Aged Pulsatile Flow / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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