| Ethnic and sex differences in the prevalence, treatment, and control of dyslipidemia among hypertensive adults in the GENOA study. | |
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MedLine Citation:
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PMID: 15226165 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Two ethnically different, community-based samples of hypertensive adults were evaluated to determine the prevalence of dyslipidemia and how often dyslipidemia is drug-treated and controlled by such treatment. METHODS: We studied 1286 non-Hispanic black hypertensive subjects from Jackson and 1070 non-Hispanic white hypertensive subjects from Rochester who participated in the Genetic Epidemiology Network of Arteriopathy study. Subjects were categorized according to presence of coronary heart disease and risk factors for coronary heart disease. RESULTS: Prevalence of dyslipidemia was significantly greater among whites than blacks (women, 64.7% vs 49.5%; and men, 78.4% vs 56.7%; P<.001 for both) and among men than women (P</=.02 in each ethnic group). Among dyslipidemic subjects, treatment with lipid-regulating drugs was significantly more common among whites than blacks (women, 25.4% vs 16.4%, P =.001; and men, 32.6% vs 12.8%; P<.001), and among whites, treatment was significantly more common among men than women (P =.03). With drug treatment, control of dyslipidemia varied from 33.9% (white men) to 51.9% (black men), but the differences among ethnic-sex groups were not statistically significant. CONCLUSIONS: Dyslipidemia is highly prevalent in hypertensive adults. Fewer than one third of these adults are drug-treated, and fewer than half of those treated achieve recommended goals. Our findings suggest that an alarming 9 of 10 dyslipidemic hypertensive adults have untreated or undertreated dyslipidemia. |
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Authors:
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John G O'Meara; Sharon L R Kardia; Jeffrey J Armon; C Andrew Brown; Eric Boerwinkle; Stephen T Turner |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Archives of internal medicine Volume: 164 ISSN: 0003-9926 ISO Abbreviation: Arch. Intern. Med. Publication Date: 2004 Jun |
Date Detail:
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Created Date: 2004-06-30 Completed Date: 2004-08-05 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372440 Medline TA: Arch Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 1313-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Pharmacy Services, Mayo Clinic and Foundation, Rochester, Minn, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult African Continental Ancestry Group Aged Antilipemic Agents / therapeutic use Biological Markers / blood Cholesterol, LDL / blood Coronary Disease / drug therapy, epidemiology, prevention & control Drug Therapy, Combination Ethnic Groups* European Continental Ancestry Group Female Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use Hyperlipidemias / drug therapy, ethnology*, prevention & control* Hypertension / drug therapy, ethnology*, prevention & control* Male Middle Aged Prevalence Risk Factors Sex Factors Treatment Outcome United States / ethnology |
| Grant Support | |
ID/Acronym/Agency:
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R01 HL53330/HL/NHLBI NIH HHS; R01 HL68737/HL/NHLBI NIH HHS; U01 HL54457/HL/NHLBI NIH HHS; U01 HL54464/HL/NHLBI NIH HHS; U01 HL54481/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antilipemic Agents; 0/Biological Markers; 0/Cholesterol, LDL; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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