Document Detail


Ethnic differences in selective neonatal BCG immunisation: white British children miss out.
MedLine Citation:
PMID:  16384882     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Tuberculosis (TB) is a re-emerging problem, especially in the larger cities of Western Europe. Selective neonatal BCG vaccination is recommended for infants at risk of TB in the UK. Neonatal BCG is safe and effective, with an overall protective value of 75%. This study aimed to assess BCG rates among at risk infants in Cardiff and the Vale of Glamorgan, South Wales in the year 2003. METHODS: A cohort of infants at risk for TB was identified from demographic data stored on a computerised maternity activity database. A manual search of immunisation records determined overall rates and the rates for infants belonging to various ethnic groups. RESULTS: Of 5308 infants born in 2003, 514 (9.6%) were at risk of TB; 423 (82.2%) of these infants were referred postnatally for BCG vaccination and 391 received it. Twenty six of the 41 at risk white British infants missed having a BCG vaccination compared with 47 of 288 Asian infants and seven of 39 black African babies. The rate of BCG vaccination among white British infants was 36.5% compared with 83.6% for Asian infants from the Indian subcontinent (chi(2) = 7.25, p<0.01) and 82% for black African infants (chi(2) = 4.48, p<0.05). CONCLUSIONS: The overall BCG rate among at risk infants in Cardiff was 76% during the study period. The vaccination rate was poor among white British infants compared with other ethnic groups. Enhanced awareness of health professionals to recognise the need for vaccinating certain white children at risk of TB is essential to improve BCG coverage in an increasingly multiethnic population.
Authors:
R Srinivasan; L Menon; P Stevens; I Campbell; M Alfaham
Publication Detail:
Type:  Journal Article     Date:  2005-12-29
Journal Detail:
Title:  Thorax     Volume:  61     ISSN:  0040-6376     ISO Abbreviation:  Thorax     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-03-06     Completed Date:  2006-04-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0417353     Medline TA:  Thorax     Country:  England    
Other Details:
Languages:  eng     Pagination:  247-9     Citation Subset:  IM    
Affiliation:
Department of Child Health, Llandough Hospital, Cardiff CF64 2XX, UK. ramsriniv@doctors.org.uk
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MeSH Terms
Descriptor/Qualifier:
Africa / ethnology
Asia / ethnology
BCG Vaccine*
Cohort Studies
European Continental Ancestry Group / ethnology
Humans
Immunization / utilization*
Infant
Patient Acceptance of Health Care / ethnology*
Risk Factors
Tuberculosis / ethnology,  prevention & control*
Wales / epidemiology
Chemical
Reg. No./Substance:
0/BCG Vaccine
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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