Document Detail


Ethnic differences in intraocular pressure reduction and anterior segment biometric parameters following cataract surgery by phacoemulsification.
MedLine Citation:
PMID:  23146132     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: To determine the association between ethnicity and changes in intraocular pressure (IOP) and anterior segment biometric parameters following cataract surgery by phacoemulsification in nonglaucomatous subjects. DESIGN: Prospective clinical cohort study. PARTICIPANTS: Caucasian and Asian subjects. METHODS: Anterior segment optical coherence tomography (ASOCT) scans under dark conditions and IOP measurements were obtained preoperatively and at 3 months following cataract surgery by phacoemulsification. The Zhongshan Angle Assessment Program calculated anterior chamber depth (ACD), anterior chamber volume (ACV), angle opening distance (AOD), and angle recess area (ARA) from the ASOCT images. The percentage changes in IOP, ACD, ACV, AOD, and ARA following cataract surgery by phacoemulsification were modeled as a function of ethnicity using linear mixed-effects regression, a likelihood ratio test function that adjusted for age, sex, and the use of both eyes in the same subject to determine the association between ethnicity and postoperative outcomes. MAIN OUTCOME MEASURES: intraocular pressure, anterior chamber depth, anterior chamber volume, angle opening distance, and angle recess area. RESULTS: 50 Asian and 23 Caucasian nonglaucomatous eyes were analyzed. Postoperative decrease in IOP and increases in AOD, ACD, ACV, and ARA were observed within each ethnic group (P<0.005). However, the percent changes in IOP, AOD, ACD, ACV, and ARA did not differ between groups (P>0.05). CONCLUSIONS: In this study, regardless of ethnic classification, subjects who received cataract surgery by phacoemulsification experienced a significant postoperative decrease in IOP and increases in AOD, ACD, ACV, and ARA. The percent changes in postoperative outcomes did not differ significantly by ethnicity.
Authors:
Roland Y Lee; Toshimitsu Kasuga; Qi N Cui; Guofu Huang; Sophia Y Wang; Shan C Lin
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-13
Journal Detail:
Title:  Clinical & experimental ophthalmology     Volume:  -     ISSN:  1442-9071     ISO Abbreviation:  Clin. Experiment. Ophthalmol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100896531     Medline TA:  Clin Experiment Ophthalmol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors. Clinical and Experimental Ophthalmology © 2012 Royal Australian and New Zealand College of Ophthalmologists.
Affiliation:
Department of Ophthalmology, University of California, San Francisco, California, USA.
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