Document Detail


Ethnic differences in intraocular pressure reduction and changes in anterior segment biometric parameters following cataract surgery by phacoemulsification.
MedLine Citation:
PMID:  23146132     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: To determine the association between ethnicity and changes in intraocular pressure and anterior segment biometric parameters following cataract surgery by phacoemulsification in nonglaucomatous subjects.
DESIGN: Prospective clinical cohort study.
PARTICIPANTS: Caucasian and Asian subjects.
METHODS: Customized software was used to calculate parameters from anterior segment optical coherence tomography images obtained preoperatively and at 3 months following cataract surgery by phacoemulsification. The percentage changes in intraocular pressure and anterior segment biometric parameters following cataract surgery by phacoemulsification were modelled as a function of ethnicity using linear mixed-effects regression, a likelihood ratio test function that adjusted for age, sex and the use of both eyes in the same subject, to determine the association between ethnicity and postoperative outcomes.
MAIN OUTCOME MEASURES: Intraocular pressure, angle opening distance, anterior chamber depth, anterior chamber volume, and angle recess area.
RESULTS: Fifty Asian and 23 Caucasian nonglaucomatous eyes were analysed. Postoperative decrease in intraocular pressure and increases in angle opening distance, anterior chamber depth, anterior chamber volume and angle recess area were observed within each ethnic group (P < 0.005). The percent changes in intraocular pressure, angle opening distance, anterior chamber depth, anterior chamber volume and angle recess area did not differ between ethnic groups (P > 0.05).
CONCLUSIONS: In this study, regardless of ethnic classification, subjects who received cataract surgery by phacoemulsification experienced a significant postoperative decrease in intraocular pressure and increases in angle opening distance, anterior chamber depth, anterior chamber volume and angle recess area. The percent changes in postoperative outcomes did not differ significantly by ethnicity.
Authors:
Roland Y Lee; Toshimitsu Kasuga; Qi N Cui; Guofu Huang; Sophia Y Wang; Shan C Lin
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-12-19
Journal Detail:
Title:  Clinical & experimental ophthalmology     Volume:  41     ISSN:  1442-9071     ISO Abbreviation:  Clin. Experiment. Ophthalmol.     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-26     Completed Date:  2014-01-10     Revised Date:  2014-09-03    
Medline Journal Info:
Nlm Unique ID:  100896531     Medline TA:  Clin Experiment Ophthalmol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  442-9     Citation Subset:  IM    
Copyright Information:
© 2012 The Authors. Clinical and Experimental Ophthalmology © 2012 Royal Australian and New Zealand College of Ophthalmologists.
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MeSH Terms
Descriptor/Qualifier:
Aged
Anterior Eye Segment / physiopathology*
Asian Americans / ethnology*
Axial Length, Eye
Biometry
Cataract / ethnology*,  physiopathology
Ethnic Groups
European Continental Ancestry Group / ethnology*
Female
Humans
Intraocular Pressure / physiology*
Lens Implantation, Intraocular*
Male
Phacoemulsification*
Postoperative Complications
Prospective Studies
Tomography, Optical Coherence
Tonometry, Ocular
Grant Support
ID/Acronym/Agency:
NIH-NEI EY002162/EY/NEI NIH HHS
Comments/Corrections
Comment In:
Clin Experiment Ophthalmol. 2014 Jul;42(5):508; quiz 509-10   [PMID:  24304665 ]
Clin Experiment Ophthalmol. 2014 Jul;42(5):507   [PMID:  24304636 ]
Clin Experiment Ophthalmol. 2013 Jul;41(5):425-6   [PMID:  23800000 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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