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Ethnic differences in drug utilization pattern during pregnancy: a cross-sectional study.
MedLine Citation:
PMID:  23350574     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective to investigate differences in exposure to medications in a cohort of multi-ethnic pregnant women. Methods 641 pregnant women of Western, Arab/Turkish and "other origins" participated in this cross-sectional study using a questionnaire in a university hospital in Brussels, Belgium. Assessment of the drug safety was done using the food and drug administration (FDA) risk classification system. Data analysis was performed using SPSS. Results In overall cohort, 83.8% used at least one preparation (including multivitamins) during pregnancy and 37.0% of women used at least one drug (excluding multivitamins). Significantly more Western women (43.7%) used one or more medications compared to Arab/Turkish women (28.7%;p=0.000). This difference in exposure was most pronounced for over-the-counter drugs for occasional and pregnancy-related complaints, and was observed for potentially unsafe drugs or drugs with unknown safety. None of the women reported use of FDA X category drugs. Conclusions The use of drugs known to be harmful was not observed but a higher prevalence of exposure to potentially harmful drugs (FDA C/D) was found among Western women who also consumed more over-the-counter drugs. This highlights the need for cautious prescribing for women in the fertile age in general and for continuous monitoring of medication use during pregnancy.
Authors:
M A Baraka; S Steurbaut; D Coomans; A G Dupont
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-28
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Pharmacology. Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Laarbeeklaan 103, Belgium.
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