Document Detail

Ethnic Differences in Atrial Fibrillation Identified Using Implanted Cardiac Devices.
MedLine Citation:
PMID:  23356818     Owner:  NLM     Status:  Publisher    
Ethnic Difference in Atrial Fibrillation Incidence. Introduction: Atrial fibrillation (AF) is suggested to be less common among black and Asian individuals, which could reflect bias in symptom reporting and access to care. In the Asymptomatic AF and Stroke Evaluation in Pacemaker Patients and the AF Reduction Atrial Pacing Trial (ASSERT), patients with hypertension but no history of AF had AF recorded via an implanted pacemaker or defibrillator, thus allowing both symptomatic and asymptomatic AF incidence to be determined without ascertainment bias. Methods and Results: The ASSERT enrolled 2,580 patients in 23 countries in North America, Europe, and Asia. AF was defined as device-recorded AF episodes >190/min, lasting either for >6 minutes or >6 hours in duration. All ethnic groups with >50 patients were enrolled. Ethnic groups studied include Europeans (n = 1900), black Africans (n = 73), Chinese (n = 89), and Japanese (n = 105) patients. Compared to Europeans, black Africans had more risk factors for AF such as heart failure (27.8 vs 14.6%) and diabetes (41.7 vs 26.3%). At 2.5 years follow-up, all 3 non-European races had a lower incidence of AF (8.3%, 10.1%, and 9.5% vs 18.0%, respectively, for AF>6 minutes, P < 0.006). When adjusted for baseline difference, Chinese had a lower incidence of AF > 6 minutes (P < 0.007), and Japanese and black Africans had a lower incidence of AF > 6 hours (P < 0.04 and P = 0.057, respectively). Conclusions: Black Africans, Chinese, and Japanese had lower incidence of AF compared to Europeans. In the case of black Africans, this is despite an increased prevalence of AF risk factors. (J Cardiovasc Electrophysiol, Vol. pp. 1-7).
Chu-Pak Lau; T David Gbadebo; Stuart J Connolly; Isabelle C VAN Gelder; Alessandro Capucci; Michael R Gold; Carsten W Israel; Carolos A Morillo; Chung-Wah Siu; Haruhiko Abe; Mark Carlson; Hung-Fat Tse; Stefan H Hohnloser; Jeff S Healey;
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-28
Journal Detail:
Title:  Journal of cardiovascular electrophysiology     Volume:  -     ISSN:  1540-8167     ISO Abbreviation:  J. Cardiovasc. Electrophysiol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9010756     Medline TA:  J Cardiovasc Electrophysiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 Wiley Periodicals, Inc.
Queen Mary Hospital, Department of Medicine, University of Hong Kong, Hong Kong, China University of Tennessee Erlanger Cardiology, UT College of Medicine, Chattanooga, Tennessee, USA Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada University of Groningen, University Medical Center Groningen, Groningen, the Netherlands Clinical di Cardiologia, Università Politecnica delle Marche, Ancona, Italy Medical University of South Carolina, Charleston, South Carolina, USA J.W. Goethe University, Frankfurt, Germany Division of Cardiology, University of Occupational and Environmental Health, Kitakyushu, Japan St. Jude Medical, Sylmar, CA, USA, and Zaventem, Belgium.
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