Document Detail


Ethinyl oestradiol and D-norgestrel is an effective emergency postcoital contraceptive: a report of its use in 1,200 patients in a family planning clinic.
MedLine Citation:
PMID:  3228408     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe a prospective study of 1,200 patients using the Yuzpe regimen of hormonal postcoital contraception. There was an 85% follow-up rate, and of the 1,015 patients followed there were 13 pregnancies, giving a pregnancy rate of 1.3%. The number of expected pregnancies at mid-cycle was reduced by 83%; 12 of the 13 pregnancies went on to abortion. The patients were young: 86% were under 25, and 10% were under 15. The most frequent reason for presentation was that no contraception had been used (57%). All patients received an antiemetic; 57% experienced no side-effects, 28% had some nausea and 9.6% some vomiting. It is concluded that this is a safe form of emergency contraception, which is an effective way of reducing the number of unwanted pregnancies, especially in the very young.
This prospective study comprised 1200 patients who were using the Yuzpe regimen of postcoital hormonal contraception. There was an 85% follow-up rate, and of the 1015 patients followed, there were 13 pregnancies for a pregnancy rate of 1.3%. The number of expected pregnancies at midcycle was reduced by 83%; 12 of the 13 pregnancies went on to abortion. The patients were young--86% were under age 25 and 10% were under age 15. The most frequent reason for presentation was that there had been no contraception used (57%). All patients received an antiemetic and 57% experienced no side effects while 28% had some nausea, and 9.6% had vomiting. It is concluded that this is a safe form of emergency contraception, which is thus an effective way to reduce the number of unwanted pregnancies, especially in the very young.
Authors:
S N Bagshaw; D Edwards; A K Tucker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Australian & New Zealand journal of obstetrics & gynaecology     Volume:  28     ISSN:  0004-8666     ISO Abbreviation:  Aust N Z J Obstet Gynaecol     Publication Date:  1988 May 
Date Detail:
Created Date:  1989-04-06     Completed Date:  1989-04-06     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0001027     Medline TA:  Aust N Z J Obstet Gynaecol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  137-40     Citation Subset:  IM; J    
Affiliation:
Christchurch Branch, Family Planning Association, New Zealand.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Ambulatory Care Facilities
Contraceptives, Postcoital*
Contraceptives, Postcoital, Hormonal*
Drug Administration Schedule
Emergencies
Ethinyl Estradiol / administration & dosage*,  adverse effects
Family Planning Services
Female
Humans
Nausea / chemically induced
Norgestrel / administration & dosage*,  adverse effects
Prospective Studies
Vomiting / chemically induced
Chemical
Reg. No./Substance:
0/Contraceptives, Postcoital; 0/Contraceptives, Postcoital, Hormonal; 57-63-6/Ethinyl Estradiol; 6533-00-2/Norgestrel

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