Document Detail

Ethical issues in cooperative cancer therapy trials from a statistical viewpoint. I. A general overview.
MedLine Citation:
PMID:  4037244     Owner:  NLM     Status:  MEDLINE    
In conducting collaborative cancer therapy trials, investigators have an obligation to answer relevant and realistic research questions, while providing the patient with quality treatment. They should participate only in well-conceived, well-designed protocols. Their patients should follow the protocol as closely as possible. Protocol violations are admissible only in extreme cases, instances in which the patient's well-being is clearly best served by this violation. The participating clinicians have the obligation to submit quality and timely data. Finally, the results of each study must be written up in such a fashion that the reader has a clear understanding of the goals and outcomes of the trial.
J J Shuster; J P Krischer; J M Boyett
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of pediatric hematology/oncology     Volume:  7     ISSN:  0192-8562     ISO Abbreviation:  Am J Pediatr Hematol Oncol     Publication Date:  1985  
Date Detail:
Created Date:  1985-10-15     Completed Date:  1985-10-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7908071     Medline TA:  Am J Pediatr Hematol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  57-63     Citation Subset:  E; IM    
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MeSH Terms
Clinical Trials as Topic / methods*
Control Groups
Ethics Committees, Research
Ethics, Medical*
Informed Consent
Neoplasms / therapy*
Patient Selection
Research Design
Research Subjects
Social Responsibility
Grant Support
U-10 CA 29139-03/CA/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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