| Ethical aspects of soft tissue engineering for congenital birth defects in children--what do experts in the field say? | |
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MedLine Citation:
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PMID: 20163208 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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This article is part of the EuroSTEC project, which aims at developing tissue engineering-based treatments for structural disorders present at birth. EuroSTEC is positioned at the intersection of three areas with their own ethical issues: (1) regenerative medicine, (2) research with pregnant women and fetuses, and (3) research with neonates. Because of the overlap of these three areas in this project, we can expect to be confronted with new ethical challenges. To be able to respond adequately and timely to current and possible future ethical issues, a prospective and anticipatory ethical analysis is essential. To obtain a first survey of ethical issues that might arise during the different phases of the project, the Delphi method was used. The professionals directly involved in the EuroSTEC project were questioned about their views on possible ethical issues. The first round yielded 27 ethical issues, which the respondents were asked to prioritize in the second round. For the fundamental research phase, issues deemed most important were privacy and informed consent of the tissue donor. For the animal experimentation phase, three issues were mentioned (in order of decreasing priority): the suffering of animals, the use of animals as means to an end, and the limited adequacy of the animal models. Issues that were deemed most important during the clinical (trial) phase pertained to the problem of weighing risks and benefits for the fetus/child and the pregnant woman. |
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Authors:
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Anke J M Oerlemans; Catarina H C M L Rodrigues; Marian A Verkerk; Paul P van den Berg; Wim J M Dekkers |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Tissue engineering. Part B, Reviews Volume: 16 ISSN: 1937-3376 ISO Abbreviation: Tissue Eng Part B Rev Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101466660 Medline TA: Tissue Eng Part B Rev Country: United States |
Other Details:
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Languages: eng Pagination: 397-403 Citation Subset: IM |
Affiliation:
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Scientific Institute for Quality of Healthcare, Section Ethics, Philosophy, and History of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. a.oerlemans@iq.umcn.nl |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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