Document Detail


Ethanol and food pellet self-administration by baboons.
MedLine Citation:
PMID:  9744847     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During daily 23-h sessions, baboons had concurrent access to food pellets and an oral ethanol/dextrose solution. The effect of increasing the fixed-ratio or "cost" for pellets on pellet and fluid intake was examined when baboons had access to 2%, 4%, or 8% (w/v) ethanol. Increasing the response requirement for a pellet decreased pellet intake. The rate of decrease in pellet intake with increasing pellet cost was unaffected by the availability of ethanol solutions, which were either self-administered or given in investigator-planned doses. Increasing the response cost for pellets significantly increased self-administration of 4% ethanol. The effect of increasing the cost for fluid on fluid and pellet intake was examined when baboons had access to vehicle, 4% or 8% (w/v) ethanol. Although the total daily number of fluid deliveries was significantly greater when 4% ethanol was available, compared to vehicle, increasing the cost for a fluid delivery to 32 responses and above decreased intake of all three fluids similarly. Increasing the cost of ethanol did not affect food intake.
Authors:
R W Foltin
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Alcohol (Fayetteville, N.Y.)     Volume:  16     ISSN:  0741-8329     ISO Abbreviation:  Alcohol     Publication Date:  1998 Oct 
Date Detail:
Created Date:  1999-05-24     Completed Date:  1999-05-24     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8502311     Medline TA:  Alcohol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  183-8     Citation Subset:  IM    
Affiliation:
New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, USA. rwf2@columbia.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Behavior, Animal*
Ethanol / metabolism*
Food*
Male
Papio
Self Administration
Grant Support
ID/Acronym/Agency:
DA-04130/DA/NIDA NIH HHS
Chemical
Reg. No./Substance:
64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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