| Ethanol and food pellet self-administration by baboons. | |
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MedLine Citation:
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PMID: 9744847 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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During daily 23-h sessions, baboons had concurrent access to food pellets and an oral ethanol/dextrose solution. The effect of increasing the fixed-ratio or "cost" for pellets on pellet and fluid intake was examined when baboons had access to 2%, 4%, or 8% (w/v) ethanol. Increasing the response requirement for a pellet decreased pellet intake. The rate of decrease in pellet intake with increasing pellet cost was unaffected by the availability of ethanol solutions, which were either self-administered or given in investigator-planned doses. Increasing the response cost for pellets significantly increased self-administration of 4% ethanol. The effect of increasing the cost for fluid on fluid and pellet intake was examined when baboons had access to vehicle, 4% or 8% (w/v) ethanol. Although the total daily number of fluid deliveries was significantly greater when 4% ethanol was available, compared to vehicle, increasing the cost for a fluid delivery to 32 responses and above decreased intake of all three fluids similarly. Increasing the cost of ethanol did not affect food intake. |
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Authors:
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R W Foltin |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Alcohol (Fayetteville, N.Y.) Volume: 16 ISSN: 0741-8329 ISO Abbreviation: Alcohol Publication Date: 1998 Oct |
Date Detail:
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Created Date: 1999-05-24 Completed Date: 1999-05-24 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8502311 Medline TA: Alcohol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 183-8 Citation Subset: IM |
Affiliation:
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New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, USA. rwf2@columbia.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Behavior, Animal* Ethanol / metabolism* Food* Male Papio Self Administration |
| Grant Support | |
ID/Acronym/Agency:
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DA-04130/DA/NIDA NIH HHS |
| Chemical | |
Reg. No./Substance:
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64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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