| Ethane production rate in vivo is reduced with dietary restriction. | |
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MedLine Citation:
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PMID: 2384436 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Dietary restriction without malnutrition prolongs life and has a beneficial effect on age-related diseases and metabolic derangements. To test the effect of food restriction on ethane production rate, ethane exhalation was measured in rats with partial food restriction. Ethane production rate in room air in rats fed 60% of food consumed by ad libitum-fed animals for 2 wk was significantly reduced (3.50 +/- 0.25 vs. 5.21 +/- 0.34 pmol.min-1.100 g body wt-1, P less than 0.01). In 100% oxygen, ethane production in food-restricted rats was not different from that of ad libitum-fed rats (21.81 +/- 1.25 vs. 19.57 +/- 1.89 pmol.min-1.100 g-1). Fifteen hours of fasting compared with ad libitum feeding reduced ethane production modestly in room air (4.37 +/- 0.45 vs. 5.21 +/- 0.34 pmol.min-1.100 g-1) and more significantly in 100% oxygen (12.37 +/- 0.78 vs. 19.57 +/- 1.89 pmol.min-1.100 g-1). Thus, in 100% oxygen, 15 h of fasting, compared with ad libitum feeding, resulted in an approximately 40% decrease in ethane production rate. It is concluded that short-term food restriction significantly reduces ethane exhalation rate in rats when measured in room air. |
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Authors:
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M P Habib; F Dickerson; A D Mooradian |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: 68 ISSN: 8750-7587 ISO Abbreviation: J. Appl. Physiol. Publication Date: 1990 Jun |
Date Detail:
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Created Date: 1990-09-18 Completed Date: 1990-09-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2588-90 Citation Subset: IM |
Affiliation:
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Department of Medicine, College of Medicine, University of Arizona, Tucson. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Diet* Energy Intake Ethane / metabolism* Fasting Free Radicals Lipid Peroxidation Male Rats Rats, Inbred F344 |
| Chemical | |
Reg. No./Substance:
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0/Free Radicals; 74-84-0/Ethane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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