| Etanercept-related extensive pulmonary nodulosis in a patient with rheumatoid arthritis. | |
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MedLine Citation:
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PMID: 17610313 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Although nodulosis is a common extraarticular manifestation of rheumatoid arthritis, accelerated pulmonary nodulosis is a rare event. The etiology of rheumatoid nodules is still unknown. Nodulosis is not necessarily associated with active joint inflammation, suggesting different pathogenic mechanisms for nodule formation and synovial tissue inflammation. We describe a patient with extensive pulmonary nodulosis, probably related to etanercept treatment. Our case emphasizes the need for careful monitoring for adverse events during treatment with biologicals, especially since the differential diagnosis often includes a broad spectrum of diseases. |
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Authors:
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Annelies van Ede; Alfons den Broeder; Michiel Wagenaar; Piet van Riel; Marjonne C W Creemers |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2007-06-15 |
Journal Detail:
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Title: The Journal of rheumatology Volume: 34 ISSN: 0315-162X ISO Abbreviation: J. Rheumatol. Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-07-05 Completed Date: 2007-08-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7501984 Medline TA: J Rheumatol Country: Canada |
Other Details:
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Languages: eng Pagination: 1590-2 Citation Subset: IM |
Affiliation:
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Department of Rheumatology, University Medical Centre Nijmegen, Nijmegen, The Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Inflammatory Agents
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therapeutic use Antirheumatic Agents / adverse effects* Arthritis, Rheumatoid* Azathioprine / therapeutic use Drug Therapy, Combination Humans Immunoglobulin G / adverse effects* Immunosuppressive Agents / therapeutic use Male Middle Aged Prednisone Radiography, Thoracic Receptors, Tumor Necrosis Factor Rheumatoid Nodule / chemically induced*, drug therapy, pathology Tomography, X-Ray Computed Withholding Treatment |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Antirheumatic Agents; 0/Immunoglobulin G; 0/Immunosuppressive Agents; 0/Receptors, Tumor Necrosis Factor; 185243-69-0/TNFR-Fc fusion protein; 446-86-6/Azathioprine; 53-03-2/Prednisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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