Document Detail


Etamsylate (Dicynone) reduces aqueous humor formation and intraocular pressure in rabbits.
MedLine Citation:
PMID:  6646628     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The rate of aqueous humor production (measured by the clearance of 125I-labeled albumin administered into the anterior chamber) and the intraocular pressure (measured via an electronic transducer) fell after subconjunctival infection of 37 mg (0.3 ml) of etamsylate (Dicynone) in rabbits. The differences between treated and untreated animals with respect to both variables were statistically significant. It is conjectured that the action of etamsylate in lowering intraocular pressure may be mediated at least in part by its reduction of aqueous humor formation.
Authors:
M Jozsa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ophthalmic research     Volume:  15     ISSN:  0030-3747     ISO Abbreviation:  Ophthalmic Res.     Publication Date:  1983  
Date Detail:
Created Date:  1984-01-07     Completed Date:  1984-01-07     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0267442     Medline TA:  Ophthalmic Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  265-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Aqueous Humor / drug effects*,  secretion
Benzenesulfonates / pharmacology*
Conjunctiva
Ethamsylate / pharmacology*
Female
Injections
Intraocular Pressure / drug effects*
Male
Rabbits
Serum Albumin, Radio-Iodinated / administration & dosage
Chemical
Reg. No./Substance:
0/Benzenesulfonates; 0/Serum Albumin, Radio-Iodinated; 2624-44-4/Ethamsylate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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