Document Detail


Estrogen and progesterone in breast and gynecologic cancers. Etiology, therapeutic role, and hormone replacement.
MedLine Citation:
PMID:  7936544     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cancers of the endometrium, ovary, and breast share common risk factors, including obesity, high fat diet, and late menopause as well as an increased risk with a family and personal history of any of these cancers. Despite an extensive literature investigating the role of estrogen and progesterone in these malignancies, the exact etiologic capacity of these hormones is not yet determined. Until current studies mature, assessment of the possible risks and known benefits is the only platform on which to base treatment decisions for the individual patient.
Authors:
F G Nason; B E Nelson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Obstetrics and gynecology clinics of North America     Volume:  21     ISSN:  0889-8545     ISO Abbreviation:  Obstet. Gynecol. Clin. North Am.     Publication Date:  1994 Jun 
Date Detail:
Created Date:  1994-11-21     Completed Date:  1994-11-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8709551     Medline TA:  Obstet Gynecol Clin North Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  245-70     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Massachusetts Medical School, Worcester.
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MeSH Terms
Descriptor/Qualifier:
Breast Neoplasms* / etiology,  therapy
Endometrial Neoplasms* / etiology,  therapy
Estrogen Replacement Therapy* / adverse effects,  contraindications
Estrogens / physiology*,  therapeutic use
Female
Genital Neoplasms, Female / etiology,  therapy
Humans
Ovarian Neoplasms* / etiology,  therapy
Progesterone / physiology*,  therapeutic use
Risk Assessment
Risk Factors
Chemical
Reg. No./Substance:
0/Estrogens; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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