Document Detail

Estrogen-induced severe acute pancreatitis in a male.
MedLine Citation:
PMID:  15365202     Owner:  NLM     Status:  MEDLINE    
CONTEXT: Acute pancreatitis is related to drugs in 1.4-2% of cases. Estrogens are an uncommon but well-known risk factor of pancreatitis in women and men with pre-existing hyperlipidemia. CASE REPORT: We report the case of a 37-year-old man with covert hypertriglyceridemia who developed a severe life-threatening pancreatitis strongly associated with estrogen therapy preparatory to sex change surgery, characterized by a massive triglyceride level, pancreatic insufficiency and multiple organ failure at the time of the diagnosis. Other causes of the disease were ruled out. CONCLUSIONS: To our knowledge, this is the first description of severe necrotizing estrogen-induced pancreatitis in a male. Baseline abnormal triglyceride levels should be checked by physicians before starting estrogen therapy in women and men.
Elisa Perego; Alberto Scaini; Fabrizio Romano; Claudio Franciosi; Franco Uggeri
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2004-09-10
Journal Detail:
Title:  JOP : Journal of the pancreas     Volume:  5     ISSN:  1590-8577     ISO Abbreviation:  JOP     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-14     Completed Date:  2005-05-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101091810     Medline TA:  JOP     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  353-6     Citation Subset:  IM    
Department of Surgery, San Gerardo Hospital, University of Milano-Bicocca, Monza, MI, Italy.
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MeSH Terms
Acute Disease
Estrogens / adverse effects*
Pancreatitis / chemically induced*
Reg. No./Substance:

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