Document Detail

Estrogen, exercise, and the skeleton.
MedLine Citation:
PMID:  22034104     Owner:  NLM     Status:  In-Data-Review    
Patterns of variation in bone size and shape provide crucial data for reconstructing hominin paleobiology, including ecogeographic adaptation, life history, and functional morphology. Measures of bone strength, including robusticity (diaphyseal thickness relative to length) and cross-sectional geometric properties such as moments of area, are particularly useful for inferring behavior because bone tissue adapts to its mechanical environment.1-4, 5 Particularly during skeletal growth, exercise-induced strains can stimulate periosteal modeling so that, to some extent, bone thickness reflects individual behavior. Thus, patterns of skeletal robusticity have been used to identify gender-based activity differences, temporal shifts in mobility, and changing subsistence strategies.6-9, 10 Although there is no doubt that mechanical loading leaves its mark on the skeleton, less is known about whether individuals differ in their skeletal responses to exercise. For example, the potential effects of hormones or growth factors on bone-strain interactions are largely unexplored. If the hormonal background can increase or decrease the effects of exercise on skeletal robusticity, then the same mechanical loads might cause different degrees of bone response in different individuals.11 Here I focus on the role of the hormone estrogen in modulating exercise-induced changes in human bone thickness.
Maureen J Devlin
Related Documents :
3898944 - Slope of the dose-response curve to inhaled histamine and methacholine and pc20 in subj...
3341614 - Incorporation and analysis of ultrasonically nebulized distilled water challenges in an...
17379494 - The bronchoprotective effect of deep inspiration is flow rate dependent.
1923664 - Spontaneous changes in bronchial responsiveness in children and adolescents: an 18-mont...
20044704 - Effects of a wobble board-based therapeutic exergaming system for balance training on d...
7758214 - Quantitative determination of faecal fat, nitrogen and water by means of a spectrophoto...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Evolutionary anthropology     Volume:  20     ISSN:  1520-6505     ISO Abbreviation:  Evol. Anthropol.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-10-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306331     Medline TA:  Evol Anthropol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  54-61     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Wiley Periodicals, Inc.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Stone tool analysis and human origins research: Some advice from uncle Screwtape.
Next Document:  Sexual conflict in primates.