Document Detail


Estrano[17,16-e]pyrimidine-peptide conjugates.
MedLine Citation:
PMID:  14625007     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The preparation of a steroidal heterocycle linked to the tripeptide Cys-Gly-Cys is described. Initially, an estrane-derived steroidal heterocycle containing an aminopyrimidine ring fused to the 16,17-position of the steroidal nucleus was synthesized. Thereafter, protected amino acids were coupled iteratively by the DCC method, commencing at the amino group of the aminopyrimidine unit.
Authors:
Tomohiro Matsumoto; Masataka Watanabe; Shuntaro Mataka; Thies Thiemann
Related Documents :
45267 - Aminomethyl derivatives of 1-cyclohexyl-5-alkyl- and 1-cyclohexyl-5,5-dialkylbarbituric...
17608537 - A novel isocyanide-based three-component reaction: synthesis of highly substituted 1,6-...
357117 - The biological importance of organophosphorus compounds containing a carbon-phosphorus ...
20651937 - Monofunctionalization of calix[4]arene tetracarboxylic acid at the upper rim with isoth...
21990307 - Phase ii study of the effects of ginger root extract on eicosanoids in colon mucosa in ...
5098397 - Utilization of exogenous free fatty acids for the production of very low density lipopr...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Steroids     Volume:  68     ISSN:  0039-128X     ISO Abbreviation:  Steroids     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-11-19     Completed Date:  2004-07-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404536     Medline TA:  Steroids     Country:  United States    
Other Details:
Languages:  eng     Pagination:  751-7     Citation Subset:  IM    
Affiliation:
Interdisciplinary Graduate School of Engineering Sciences, Kyushu University, Kyushu, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cysteine / chemistry
Estranes / chemistry*
Glycine / chemistry
Oligopeptides / chemical synthesis*,  chemistry
Pyrimidines / chemistry*
Steroids / chemical synthesis*,  chemistry
Chemical
Reg. No./Substance:
0/Estranes; 0/Oligopeptides; 0/Pyrimidines; 0/Steroids; 289-95-2/pyrimidine; 52-90-4/Cysteine; 56-40-6/Glycine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Hydrolytic behavior of 5alpha-hydroxy-11beta- and 5beta-hydroxy-11alpha-substituted 19-norsteroids.
Next Document:  Minocycline-induced activation of tetracycline-responsive promoter.