Document Detail

Estrano[17,16-e]pyrimidine-peptide conjugates.
MedLine Citation:
PMID:  14625007     Owner:  NLM     Status:  MEDLINE    
The preparation of a steroidal heterocycle linked to the tripeptide Cys-Gly-Cys is described. Initially, an estrane-derived steroidal heterocycle containing an aminopyrimidine ring fused to the 16,17-position of the steroidal nucleus was synthesized. Thereafter, protected amino acids were coupled iteratively by the DCC method, commencing at the amino group of the aminopyrimidine unit.
Tomohiro Matsumoto; Masataka Watanabe; Shuntaro Mataka; Thies Thiemann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Steroids     Volume:  68     ISSN:  0039-128X     ISO Abbreviation:  Steroids     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-11-19     Completed Date:  2004-07-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404536     Medline TA:  Steroids     Country:  United States    
Other Details:
Languages:  eng     Pagination:  751-7     Citation Subset:  IM    
Interdisciplinary Graduate School of Engineering Sciences, Kyushu University, Kyushu, Japan.
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MeSH Terms
Cysteine / chemistry
Estranes / chemistry*
Glycine / chemistry
Oligopeptides / chemical synthesis*,  chemistry
Pyrimidines / chemistry*
Steroids / chemical synthesis*,  chemistry
Reg. No./Substance:
0/Estranes; 0/Oligopeptides; 0/Pyrimidines; 0/Steroids; 289-95-2/pyrimidine; 52-90-4/Cysteine; 56-40-6/Glycine

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