Document Detail


Estradiol and progesterone supplementation during luteal phase improved the receptivity of the endometrium in a patient with a history of diethylstilboestrol exposure in-utero.
MedLine Citation:
PMID:  16807227     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Diethylstilboestrol (DES) exposure in-utero has been shown to have negative effects on pregnancy. DES-exposed women are at increased risk of early spontaneous pregnancy loss, ectopic gestation and infertility. DESIGN: A 34-year old woman with a 6-year history of primary infertility is presented. The patient underwent in vitro fertilization (IVF) treatment without success. To improve the quality of the endometrium following IVF treatment, E2 and progesterone supplementation was added to the usual therapeutic regimen. The pregnancy progressed uneventfully and a normal female was born. CONCLUSIONS: This case indicates that the administration of E2 and progesterone in DES-exposed women might improve endometrium receptivity and consequently pregnancy outcome.
Authors:
Dimitris Loutradis; Konstantinos Stefanidis; Erasmia Kiapekou; Evangelia Zapanti; Chrisoula Panitsa-Faflia; Aristidis Antsaklis
Related Documents :
21236487 - Ifpa meeting 2010 workshops report ii: placental pathology; trophoblast invasion; fetal...
25045927 - Risk factors of hypertensive pregnancies in women with diabetes and the influence on th...
19140277 - Chloasma--the mask of pregnancy.
21188367 - Fetal demise secondary to massive rhabdomyoma in the early second trimester of pregnancy.
17315457 - Validating a commercially available enzyme immunoassay for the determination of 17beta-...
10100077 - U46619-mediated vasoconstriction of the fetal placental vasculature in vitro in normal ...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Hormones (Athens, Greece)     Volume:  5     ISSN:  1109-3099     ISO Abbreviation:  Hormones (Athens)     Publication Date:    2006 Apr-Jun
Date Detail:
Created Date:  2006-06-29     Completed Date:  2006-12-01     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  101142469     Medline TA:  Hormones (Athens)     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  147-50     Citation Subset:  IM    
Affiliation:
First Department of Obstetrics and Gynaecology, Athens University School of Medicine, Alexandra Hospital, Athens, Greece.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Diethylstilbestrol / adverse effects*
Endometrium / drug effects*
Estradiol / therapeutic use*
Female
Humans
Hysterosalpingography / methods
Infertility / chemically induced,  drug therapy
Luteal Phase / drug effects*
Maternal Exposure / adverse effects
Pregnancy
Prenatal Exposure Delayed Effects / drug therapy*
Progesterone / therapeutic use*
Chemical
Reg. No./Substance:
50-28-2/Estradiol; 56-53-1/Diethylstilbestrol; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Insulin resistance, growth factors and cytokine levels in overweight women with breast cancer before...
Next Document:  Cooperative fluctuations point to the dimerization interface of p53 core domain.